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STATE OF EXPERIMENTAL ANIMALS’ COLON MICROBIOCENOSIS UNDER RESTRAINT STRESS
https://doi.org/10.17021/2019.14.1.54.60
Abstract
Stress as an actual medical and biological factor necessitates the study of its various consequences for the macroorganism. The article deals with chronic restraint stress effects on the experimental animals’ colon microbiota. To assess the qualitative and quantitative composition of the microbiocenosis of this biotope, biopsy specimens of the mucous membrane of the large intestine of Wistar rats were used. It was established that stress led to a significant decrease in the number of obligate representatives of the microbiota, while the content of the facultative microflora increased. Evaluation of the frequency of occurrence and the relative average of the identified genera of microorganisms showed that chronic immobilization significantly changed the values of the studied parameters in relation to opportunistic pathogenic representatives of the microbiocenosis, and also affected their correlation with obligate bacteria. The obtained data clearly demonstrate the role of stress in the dysbiosis creation.
About the Authors
A. Yu. Mukhina
Kursk State Medical University
Russian Federation
Russian Federation
O. A. Medvedeva
Kursk State Medical University
Russian Federation
Russian Federation
M. V. Svishcheva
Kursk State Medical University
Russian Federation
Russian Federation
A. V. Shevchenko
Kursk State Medical University
Russian Federation
Russian Federation
N. N. Efremova
Kursk State Medical University
Russian Federation
Russian Federation
I. I. Bobyntsev
Kursk State Medical University
Russian Federation
Russian Federation
P. V. Kalutskiy
Kursk State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Mukhina A.Yu., Medvedeva O.A., Svishcheva M.V., Shevchenko A.V., Efremova N.N., Bobyntsev I.I., Kalutskiy P.V. STATE OF EXPERIMENTAL ANIMALS’ COLON MICROBIOCENOSIS UNDER RESTRAINT STRESS. Astrakhan medical journal. 2019;14(1):54-60. (In Russ.) https://doi.org/10.17021/2019.14.1.54.60
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