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The influence of nutritional support on the conditions of patients with chronic diffuse liver diseases of toxic-alimentary etiology

https://doi.org/10.17021/1992-6499-2025-4-18-31

Abstract

The influence of nutritional support on the condition of patients suffering from chronic diffuse liver diseases of toxic- alimentary origin, including alcoholic liver disease, is being examined. The material for analysis consisted of publications by both domestic and foreign authors, which describe modern strategies of nutritional intervention, their significance in correcting protein-energy deficiency, as well as in the prevention and treatment of malnutrition and sarcopenia. The summarized results of the studies demonstrate that properly organized nutritional therapy contributes to the restoration of liver functional reserves, reduces the frequency and severity of complications, including hepatic encephalopathy, and positively affects the prognosis and quality of life of patients. An analysis of the effectiveness of various approaches was conducted – from therapeutic diets and enteral nutrition to parenteral methods – taking into account their advantages, risks, and metabolic consequences. Based on this review, the authors conclude that nutritional support should be considered an essential component of comprehensive treatment for patients with chronic diffuse liver diseases of toxic- alimentary etiology, and the development of unified standards for its administration is an important task for future clinical studies.

About the Authors

G. V. Komarov
Astrakhan State Medical University
Russian Federation

Georgii V. Komarov, Assistant Professor of the Department,

Astrakhan.



V. V. Antonyan
Astrakhan State Medical University
Russian Federation

Vitalina V. Antonyan, Dr. Sci. (Med.), Associate Professor, Head of the Department,

Astrakhan.



A. R. Umerova
Astrakhan State Medical University
Russian Federation

Adela R. Umerova, Dr. Sci. (Med.), Professor, Head of the Department,

Astrakhan.



O. P. Ostroverkhov
Astrakhan State Medical University
Russian Federation

Oleg P. Ostroverkhov, Cand. Sci. (Med.), Associate Professor of the Department,

Astrakhan.



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Review

For citations:


Komarov G.V., Antonyan V.V., Umerova A.R., Ostroverkhov O.P. The influence of nutritional support on the conditions of patients with chronic diffuse liver diseases of toxic-alimentary etiology. Astrakhan medical journal. 2025;20(4):18-31. (In Russ.) https://doi.org/10.17021/1992-6499-2025-4-18-31

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ISSN 1992-6499 (Print)