Modern biologically active suture material: problems and prospects

The aim of this study was to identify the key problems and prospects for the development of biologically active suture materials. Modern domestic and foreign literature sources on this topic were analyzed. One of the main difficulties remains the creation of a universal suture material that would combine the advantages of existing solutions without their disadvantages. Current developments, such as “Tveran” (“Volot”, Russia) or combination of polypropylene and polyglycolic acid with fluoroquinolones, show high efficiency, but their use is associated with the risk of antibiotic resistance development. This problem is becoming increasingly important due to the emergence of resistant strains of microorganisms. Additional limitations include the hydrophobicity of filaments, as well as the lack of functional groups for immobilization of active compounds on the surface of the suture material. Addressing these issues can significantly improve the efficiency and safety of suture materials.

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