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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">astmed</journal-id><journal-title-group><journal-title xml:lang="ru">Астраханский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Astrakhan medical journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1992-6499</issn><publisher><publisher-name>ФГБОУ ВО Астраханский ГМУ Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17021/1992-6499-2025-3-88-100</article-id><article-id custom-type="elpub" pub-id-type="custom">astmed-615</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДОСТИЖЕНИЯ НАУКИ В ПРАКТИКУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ACHIEVEMENTS OF SCIENCE IN PRACTICE</subject></subj-group></article-categories><title-group><article-title>Современный биологически активный шовный материал: проблемы и перспективы</article-title><trans-title-group xml:lang="en"><trans-title>Modern biologically active suture material: problems and prospects</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4213-5379</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Артѐм Михайлович, кандидат медицинских наук, доцент, доцент кафедры общей хирургии</p><p>Тверь</p></bio><bio xml:lang="en"><p>Artem M. Morozov, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department</p><p>Tver</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9657-8063</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергеев</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeev</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергеев Алексей Николаевич, доктор медицинских наук, доцент, заведующий кафедрой общей хирургии</p><p>Тверь</p></bio><bio xml:lang="en"><p>Alexey N. Sergeev, Dr. Sci. (Med.), Associate Professor, Head of the Department</p><p>Tver</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2567-6088</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аскеров</surname><given-names>Э. M.</given-names></name><name name-style="western" xml:lang="en"><surname>Askerov</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аскеров Эльшад Магомедович, кандидат медицинских наук, доцент, доцент кафедры общей хирургии</p><p>Тверь</p></bio><bio xml:lang="en"><p>Elshad M. Askerov, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department</p><p>Tver</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2989-8753</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богочанов</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogochanov</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Богочанов Владислав Сергеевич, студент</p><p>Тверь</p></bio><bio xml:lang="en"><p>Vladislav S. Bogochanov, student, Tver State Medical University</p><p>Tver</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6056-5033</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нилова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Nilova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нилова Елизавета Игоревна, студент</p><p>Тверь</p></bio><bio xml:lang="en"><p>Elizaveta I. Nilova, student, Tver State Medical University</p><p>Tver</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3176-7389</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитриева</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitrieva</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитриева Дарья Андреевна, студент</p><p>Тверь</p></bio><bio xml:lang="en"><p>Darya A. Dmitrieva, student, Tver State Medical University</p><p>Tver</p></bio><email xlink:type="simple">ammorozovv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тверской государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tver State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>29</day><month>11</month><year>2025</year></pub-date><volume>20</volume><issue>3</issue><fpage>88</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Морозов А.М., Сергеев А.Н., Аскеров Э.M., Богочанов В.С., Нилова Е.И., Дмитриева Д.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Морозов А.М., Сергеев А.Н., Аскеров Э.M., Богочанов В.С., Нилова Е.И., Дмитриева Д.А.</copyright-holder><copyright-holder xml:lang="en">Morozov A.M., Sergeev A.N., Askerov E.M., Bogochanov V.S., Nilova E.I., Dmitrieva D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.astmedj.ru/jour/article/view/615">https://www.astmedj.ru/jour/article/view/615</self-uri><abstract><p>Целью настоящего исследования было выявление ключевых проблем и перспектив развития биологически активных шовных материалов. Проведѐн анализ современных отечественных и зарубежных литературных источников по данной теме. Одной из основных трудностей остаѐтся создание универсального шовного материала, который сочетал бы преимущества существующих решений при отсутствии их недостатков. Текущие разработки, такие как «Тверан» («Волоть», Россия) или сочетание полипропилена и полигликоевой кислоты с фторхинолонами, показывают высокую эффективность, однако их использование сопряжено с риском развития антибиотикорезистентности. Данная проблема становится всѐ более актуальной вследствие появления устойчивых штаммов микроорганизмов. Дополнительные ограничения включают гидрофобность нитей, а также отсутствие функциональных групп для иммобилизации активных соединений на поверхности шовного материала. Решение данных вопросов может значительно повысить эффективность и безопасность шовных материалов.</p></abstract><trans-abstract xml:lang="en"><p>The aim of this study was to identify the key problems and prospects for the development of biologically active suture materials. Modern domestic and foreign literature sources on this topic were analyzed. One of the main difficulties remains the creation of a universal suture material that would combine the advantages of existing solutions without their disadvantages. Current developments, such as “Tveran” (“Volot”, Russia) or combination of polypropylene and polyglycolic acid with fluoroquinolones, show high efficiency, but their use is associated with the risk of antibiotic resistance development. This problem is becoming increasingly important due to the emergence of resistant strains of microorganisms. Additional limitations include the hydrophobicity of filaments, as well as the lack of functional groups for immobilization of active compounds on the surface of the suture material. Addressing these issues can significantly improve the efficiency and safety of suture materials.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>шовный материал</kwd><kwd>хирургия</kwd><kwd>«Капрогент»</kwd><kwd>«Никант»</kwd><kwd>«Тверан»</kwd><kwd>биологически активный шовный материал</kwd><kwd>антибиотикорезистентность</kwd><kwd>полипропилен</kwd><kwd>фторхинолоны</kwd></kwd-group><kwd-group xml:lang="en"><kwd>suture material</kwd><kwd>surgery</kwd><kwd>“Caprogent”</kwd><kwd>“Nikant”</kwd><kwd>“Tveran”</kwd><kwd>biologically active suture material</kwd><kwd>antibiotic resistance</kwd><kwd>polypropylene</kwd><kwd>fluoroquinolones</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Khil M. 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