Optimization of diagnosis and treatment of acute enteral insufficiency in peritonitis. Literature review
https://doi.org/10.17021/1992-6499-2025-3-34-46
Abstract
Acute enteral insufficiency in children is a serious clinical condition that requires in-depth study in the context of modern medical research. The urgency of the problem is due to the high frequency of this condition, as well as its significant impact on the quality of life of patients and the prognosis of diseases of the gastrointestinal tract. Research in this area contributes to the development of effective methods of diagnosis, treatment and prevention, which is crucial for improving outcomes in children with acute enteral insufficiency.
Goal. To systematize existing research and identify the main trends, achievements and gaps in current knowledge about intestinal insufficiency in children. To analyze the literature sources covering the problem of intestinal insufficiency in children to a depth of about twenty years to identify available data on optimizing algorithms for the diagnosis and treatment of this pathological condition in children.
Materials and Methods. A comprehensive search was conducted to select relevant literature sources, including specialized databases such as PubMed and Scopus, various medical journals, and other resources. The search criteria included publications published between 2005 and 2024 written in English and Russian, focusing on key aspects of adult intestinal insufficiency. Peer-reviewed scientific articles, dissertations, monographs, and review articles were considered for inclusion.
Results. Modern medicine has achieved significant success in studying intestinal insufficiency. However, the key aspects of its pathogenesis in children remain incomplete, making it difficult to ensure 100 % effectiveness of applied therapeutic methods.
Conclusion: Although surgery in Russia has great opportunities, diagnosis of intestinal insuffiency remains a difficult and time-consuming task for pediatric surgeons. It is important to continue researching this area in order to better understand the causes and develop more effective treatments.
About the Authors
A. M. YunusovaРоссия
Albina M. Yunusova, Senior Laboratory Assistant, Resident of the Department
Astrakhan
A. A. Zhidovinov
Россия
Aleksey A. Zhidovinov, Dr. Sci. (Med.), Professor, Head of the Department
Astrakhan
P. E. Permyakov
Россия
Aleksandr V. Permyakov, Cand. Sci. (Med.), Associate Professor of the Department
Astrakhan
A. V. Naumov
Россия
Рavel Е. Naumov, Cand. Sci. (Med.), Assistant Professor of the Department
Astrakhan
References
1. Abu-El-Haija M., Kumar S., Quiros J. A., Balakrishnan K., Barth B., Bitton S., Eisses J. F., Foglio E. J., Fox V., Francis D., Freeman A. J., Gonska T., Grover A. S., Husain S. Z., Kumar R., Lapsia S., Lin T., Liu Q. Y., Maqbool A., Sellers Z. M., Szabo F., Uc A., Werlin S. L., Morinville V. D. Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Pancreas Committee // Journal of Pediatric Gastroenterology and Nutrition. 2018; 66(1): 159–176.
2. Rukovodstvo po neotlozhnoy khirurgii organov bryushnoy polosti = Guide to Emergency Surgery of Abdominal Organs. Ed. by V. S. Savelev. Moscow: Triada-X; 2006: 640 p. (In Russ.).
3. Kenarskaya M. V., Ivanov S. A., Korymasov E. A. Treatment of Enteral Insufficiency in Patients with Disseminated Peritonitis. Nauka i innovatsii v meditsine = Science and Innovations in Medicine. 2018; 4 (12): 31–35 (In Russ.).
4. Chepurnykh E. E., Shurygina I. A., Shurygin M. G., Dremina N. N., Trukhan I. S. A Method for Predicting Enteral Insufficiency in Acute Peritonitis. Klinicheskaya i eksperimental'naya khirurgiya. Zhurnal imeni akademika B. V. Petrovskogo = Clinical and Experimental Surgery. Journal named after Academician B. V. Petrovsky. 2023; 11, 4 (42): 17–25 (In Russ.).
5. Kirilina S. I. Chronic intestinal insufficiency as an independent risk factor for surgical treatment of degenerative diseases of the spine and large joints. Khirurgiya pozvonochnika = Spine Surgery. 2009; 3: 071–074 (In Russ.).
6. Isakov Yu. F., Razumovsky A. Yu. Detskaya khirurgiya = Pediatric Surgery. Moscow: Meditsina; 2021: 1040 p. (In Russ.).
7. Parshin D. S., Topchiev M. A., Misrikhanov M. K., Topchiev A. M., Pyatakov S. N., Chechukhina O. B., Smirnyagina E. O. Characteristics of the enteral pathobiome in disseminated purulent peritonitis complicated by acute enteric insufficiency syndrome. Sovremennyye problemy nauki i obrazovaniya = Modern problems of science and education. 2021; 4: 56 (In Russ.).
8. Karimov Sh. I., Baimakov S. R., Asrarov A. A., Karimov M. R. Ways to prevent intestinal failure syndrome in acute intestinal obstruction. Vestnik ekstrennoy meditsiny = Bulletin of Emergency Medicine. 2016; 3: 29–34 (In Russ.).
9. Zhidovinov G. I., Klimovich I. N., Popova I. S., Milovanov A. B., Al-Dowsari A. O. Clinical presentation and diagnostics of acute intestinal failure in patients with acute abdominal surgical pathology. Vestnik Volgogradskogo gosudarstvennogo meditsinskogo universiteta = Bulletin of the Volgograd State Medical University. 2004; 11: 72–75 (In Russ.).
10. Zhidovinov A. A. Faktory riska i algoritm prognozirovaniya oslozhneniy posleoperatsionnogo perioda u bol'nykh s ostroy khirurgicheskoy patologiyey organov bryushnoy polosti = Risk factors and an algorithm for predicting postoperative complications in patients with acute surgical pathology of the abdominal organs: Abstract of a Doctor of Medicine dissertation. Volgograd; 2007: 37 p. (In Russ.).
11. Zhidovinov A. A., Aleshin D. A. Method for diagnosing enteric insufficiency stages in diffuse peritonitis in an experiment. Patent No. 2317593 C1 Russian Federation, IPC G09B 23/28. No. 2006122238/14; declared 21.06.2006; published 20.02.2008 (In Russ.).
12. Shurygina I. A., Chepurnykh E. E., Dremina N. N., Shurygin M. G. Development of a scale for assessing the severity of enteral insufficiency. Sovremennye problemy nauki i obrazovaniya = Modern problems of science and education. 2021; 5: 95 (In Russ.).
13. Chiu C. J., McArdle A. H., Brown R., Scott H. J., Gurd F. N. Intestinal mucosal lesion in lowflow states. A morphological, hemodynamic, and metabolic reappraisal. Archives of Surgery. 1970; 101: 478–483.
14. Ermolov A. S., Popova T. S., Pakhomova G. V., Uteshev N. S. Sindrom kishechnoy nedostatochnosti v neotlozhnoy abdominalnoy khirurgii (ot teorii k praktike) = Intestinal insufficiency syndrome in emergency abdominal surgery (from theory to practice). Moscow; 2005: 460 p. (In Russ.).
15. Savelev V. S., Petukhov V. A. A New Direction in the Treatment of Lipid Metabolism Disorders. Trudnyy patsient = Difficult Patient. 2004; 2 (2): 3–6 (In Russ.).
16. Karaseva O. V., Utkina K. E., Gorelik A. L., Timofeeva A. V., Golikov D. E., Ivanova T. F., Roshal L. M. Appendicular Peritonitis in Children: Effective Surgical Tactics and Intensive Care. Detskaya khirurgiya = Pediatric Surgery. 2020; 2: 62–70 (In Russ.).
17. Karaseva O. V., Golikov D. E., Gorelik A. L., Kharitonova A. Yu., Tumanova M. V., Utkina K. E. Extended small-colonic intussusception in a 4-month-old child. Detskaya khirurgiya = Pediatric Surgery. 2018; 22 (5): 272–274 (In Russ.).
18. Daminov F. A., Karabaev H. K., Khakimov E. A., Avazov A. A., Arzieva G. B. Intestinal insufficiency syndrome and its correction in severely burned patients. Neotlozhnaya khirurgiya imeni I. I. Dzhanelidze = Emergency Surgery named after I. I. Dzhanelidze. 2021; S1: 20–21 (In Russ.).
19. Uc A., Husain S. Z. Pancreatitis in Children. Gastroenterology. 2019; 156 (7): 1969–1978.
20. Dibirov M. D., Isaev A. I., Magomedaliev A. M., Shikhavov A. R., Abdullaev A. A. The role of enteral therapy in the treatment of disseminated peritonitis. Infektsii v khirurgii = Infections in surgery. 2024; 22 (1): 12–16 (In Russ.).
21. Tian G., Zhu L., Chen S., Zhao Q., Jiang T. Etiology, case fatality, recurrence, and severity in pediatric acute pancreatitis: a meta-analysis of 48 studies. Pediatric Research. 2022; 91 (1): 56–63.
22. Trifanov N. A. Improving the diagnosis and treatment of patients with obstructive small intestinal obstruction: Dissertation of Candidate of Medical Sciences. Krasnodar; 2024: 150 p. (In Russ.).
23. Volkov D. V., Smolyagin A. I., Tarasenko V. S., Balpeisova A. B. Prognostic value of immunological parameters in the diagnosis of enteral insufficiency in patients with intestinal obstruction. Vestnik Uralskoy meditsinskoy akademicheskoy nauki = Bulletin of the Ural Medical Academic Science. 2011; 2–1 (35): 119–120 (In Russ.).
24. Ali-Zade S. G., Nazarov Sh. K., Kholmatov P. K., Dodikhudoev R. A. Comprehensive diagnostics and treatment methods for enteral insufficiency syndrome in patients with acute pancreatitis. Vestnik Avitsenny = Avicenna Bulletin. 2019; 21 (1); 136–140 (In Russ.).
25. Klimovich I. N., Maskin S. S., Levchenko S. A., Zemlyakov D. S., Aleksandrov V. V. Diagnosis and treatment of intestinal insufficiency syndrome in patients with acute pancreatitis (review). Sovremennyye problemy nauki i obrazovaniya = Modern problems of science and education. 2014; 5: 508 (In Russ.).
26. Fedoseyev A. V., Budarev V. N., Abu Warda F. H., Karev Yu. V., Mordvintsev Yu. P., Kuznetsov I. V., Petyushkin V. N. Optimization of treatment of patients with enteral insufficiency by correction of intestinal dysbiosis. Moskovskiy khirurgicheskiy zhurnal = Moscow Surgical Journal. 2012; 1 (23): 14–18 (In Russ.).
27. Savelev V. S., Petukhov V. A., Son D. A., Sternina L. F., Travkin A. E., Podachin P. V., Sinyakin K. I., Gostevskikh I. S., Ivanov V. V. A new method of enterosorption in intestinal insufficiency syndrome. Annaly khirurgii = Annals of Surgery. 2005; 1: 29–32 (In Russ.).
28. Mironov A. V. Sindrom kishechnoy nedostatochnosti pri rasprostranennom peritonite: diagnostika i metody enteralnoy korrektsii = Intestinal insufficiency syndrome in generalized peritonitis: diagnostics and methods of enteral correction: Dissertation of Candidate of Medical Sciences. Moscow; 2011: 156 p. (In Russ.).
29. Stets V. V., Kryukov E. V., Shestopalov A. E. Modern approaches to intensive care of abdominal sepsis. Infektsionnyye bolezni: novosti, mneniya, obucheniye = Infectious diseases: news, opinions, training. 2017; 6 (23): 106–115 (In Russ.).
30. Baimakov S. R., Boltayev Sh. Sh., Yunusov S. Sh., Risboev R. S., Zhanibekov Sh. Sh. Modern concepts of intestinal failure syndrome in acute intestinal obstruction and ways of its correction (literature review). Zhurnal teoreticheskoy i klinicheskoy meditsiny = Journal of Theoretical and Clinical Medicine. 2020; 3: 49–56 (In Russ.).
Review
For citations:
Yunusova A.M., Zhidovinov A.A., Permyakov P.E., Naumov A.V. Optimization of diagnosis and treatment of acute enteral insufficiency in peritonitis. Literature review. Astrakhan medical journal. 2025;20(3):34-46. (In Russ.) https://doi.org/10.17021/1992-6499-2025-3-34-46
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