Experimental model of chronic median abdominal hernia in pigs

The purity of testing of implants and medical equipment depends on the creation of an experimental model.

The purpose of the study: to create a chronic model of a median hernia for testing various implants or surgical techniques.

Material and methods. 23 female pigs weighing 15-20 kg underwent surgery to induce a postoperative hernia model. 2 groups were identified. To create a low-traumatic hernia model, an endoscopic stand manufactured by Kazan, an optical trocar VISIPORT 5-12 mm AutoSuture with a laparoscope were used. To test the biological implant, an autocutaneous skin was chosen (Russian patent for the invention No. 2022103233 / 09.02.2022). A hardware device (exhaust mechanism) was also tested (Russian patent for the invention No. 2022131316 / 28.07.2023).

Results. After 30 days in both groups, diastasis corresponded to hernia W3. In the first group (main 12 individuals), it averaged 13.14 ± 1.33 cm (M ± m). The hernia gate area ranged in both groups from 296.53 ± 43.32 to 666.6666 square centimeters. In the second group (11 individuals), diastasis corresponded to an average of 14.34 ± 1.33 cm (M ± m) with an area of 296.53 ± 43.32. There was no mortality in both groups. When analyzing the results during the first week, the 1st animal had a complete eventration in the lower corner of the wound, which was sutured. In three animals, suppuration of the wound with the opening of the abscesses. During the second week, one animal of the second group had local suppuration near the cutting ligature, and in three animals in which abscesses were opened, infiltrates were detected in the projection of the postoperative scar. During the third and fourth week, the presence of infiltrate in the projection of postoperative was recorded in these three animals. At the second stage of the experiment, chronic abscesses were found in these three animals before herniation after cutting out the skin flap. There were no complications in the first group.

Conclusion. The created chronic model of a minimally invasive hernia has all the elements of a W3 postoperative hernia, has fewer postoperative complications in the area of its formation, which contributes to a more favorable condition for testing implants and surgical techniques.

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