Microorganisms and peculiarities of the course of the postoperative period in patients with infective endocarditis and COVID-19

Abstract

In patients with infective endocarditis, the type and genus of microorganisms influence the course of the postoperative period. Objective – to study the structure of microorganisms isolated from blood in patients with acute infective endocarditis associated with COVID-19 and its relationship with the development of early postoperative complications. We retrospectively analyzed the case histories of 14 patients (11 men and 3 women) with acute infective endocarditis associated with COVID-19. On admission to the hospital, all patients underwent 3-fold blood sampling for microbiological studies, which were performed on bacteriological analyzers. The frequency of microorganisms’ isolation amounted to 28.57 %. The detected pathogens were represented by Gram-positive (Enterococcus faecalis) and Gramnegative bacteria (Klebsiella pneumonia and Escherichia coli). In all patients with isolated microflora the postoperative period was complicated by pneumonia and sepsis against the background of progressive cardiac and respiratory failure, its outcome was unfavorable. When comparing our own data with literature data, it was found that the frequency of microorganism’s isolation in our patients was 28.57 %, in foreign authors – 100 %; gram-positive and gram-negative bacteria were isolated in our patients, in foreign literature – gram-positive bacteria; in our patients with positive culture in 100% of cases the postoperative period was unfavorable, in foreign authors – in 40 % of cases.