Роль процессов свободно-радикального окисления в патогенезе невынашивания беременности ранних сроков

   Несмотря на уже известные патогенетические факторы и механизмы невынашивания беременности, около 50 % подобных случаев продолжают оставаться неуточненными или идиопатическими. В последние годы активно обсуждается роль оксидативного стресса в патогенезе развития многих заболеваний, в том числе женской репродуктивной системы и осложнений беременности.

   Цель обзора – проанализировать и предоставить информацию о роли процессов свободно-радикального окисления в развитии и течении беременности как в норме, так и при невынашивании, а также о возможном использовании в практической медицине биомаркеров оксидативного стресса для оценки характера патологического процесса и эффективности проводимого лечения.

   Понимание процессов повреждения клеток, вызванных оксидативным стрессом, может не только оказать неоценимую помощь в разработке персонализированного подхода к каждому конкретному случаю невынашивания беременности, но и расширить как научные, так и клинические знания в этой области медицины.

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