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ANALYSIS OF THE COURSE OF ACUTE CORONARY SYNDROME AFTER COVID-19

https://doi.org/10.48612/agmu/2022.17.4.100.108

Abstract

COVID-19 is a risk factor for the development of the acute coronary syndrome. There is no data in the literature on the terms and frequency of ACS development, and also its course after COVID-19.
The aim. To analyze the course of the acute coronary syndrome in patients after COVID-19 and to assess the role of instrumental and biochemical parameters in patients with this pathology.
Materials and methods. The study group consisted of 35 patients with acute coronary syndrome after COVID-19. The analysis of clinical, instrumental and laboratory data of patients was carried out upon admission to the hospital: anamnesis of life and illness, electro- and echocardiography, coronary angiography, values of highly sensitive troponin T and N-terminal fragment of the pro-brain natriuretic peptide. The obtained results were processed by static analysis methods.
The results. Analysis of the course of the acute coronary syndrome in patients after COVID-19 made it possible to draw the following conclusions; acute coronary syndrome developed in patients 2-8 weeks after mild COVID-19. The acute coronary syndrome was most often observed in men. The acute coronary syndrome was characterized by a Q-forming myocardial infarction, in 25 (68,6 %) patients single vascular damage of the coronary arteries was detected, in 10 (31,4 %) – multi-vascular damage of the coronary arteries; most often there was damage of the right coronary artery, anterior descending artery and combined damage of the anterior descending artery and right coronary artery. Coronary artery damage was accompanied by an increase in highly sensitive troponin T to an average of 335,0 ng/ml. Cardiomyocyte damage was associated with heart failure, as evidenced by the values of the N-terminal fragment of the pro-brain natriuretic peptide. 

About the Authors

O. V. Petrova
Federal Center of Cardiovascular Surgery
Russian Federation

Olga V. Petrova, Dr. Sci. (Med.), Head of Laboratory 

Astrakhan



D. K. Tverdokhlebova
Federal Center of Cardiovascular Surgery
Russian Federation

Diana K. Tverdokhlebova, physician clinical laboratory diagnostics 

Astrakhan



G. R. Shabanova
Federal Center of Cardiovascular Surgery
Russian Federation

Galiya R. Shabanova, physician clinical laboratory diagnostics 

Astrakhan



D. M. Nikulina
Astrakhan State Medical University
Russian Federation

Dina M. Nikulina, Dr. Sci. (Med.), Professor, Head of Department 

Astrakhan



S. A. Shashin
Astrakhan State Medical University
Russian Federation

Sergey A. Shashin, Dr. Sci. (Med.), Professor, Professor of Department 

Astrakhan



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For citations:


Petrova O.V., Tverdokhlebova D.K., Shabanova G.R., Nikulina D.M., Shashin S.A. ANALYSIS OF THE COURSE OF ACUTE CORONARY SYNDROME AFTER COVID-19. Astrakhan medical journal. 2022;17(4):100-108. (In Russ.) https://doi.org/10.48612/agmu/2022.17.4.100.108

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ISSN 1992-6499 (Print)