THE ROLE OF MICROORGANISMS IN THE DEVELOPMENT OF CHRONIC GINGIVITIS
https://doi.org/10.48612/agmu/2022.17.4.8.15
Abstract
The oral cavity is a favourable biome for the vital activity of all forms of microorganisms, which, interacting with each other, create a biofilm, thus increasing their virulence. The pathogenic potential of some microorganisms has a sufficiently pronounced character, which can be realized under various conditions, including against the background of general somatic factors. The microflora of the oral cavity in various areas is heterogeneous both in qualitative composition and quantitative. The connection between the biotopes of the oral cavity is carried out due to the oral fluid and the microorganisms in it. The most important element from the point of view of the beginning of the pathological process on the mucous membrane of the oral cavity, including the gums and the development of gingivitis, is the dental plaque, with the formation of which begins the process of changing the species diversity of microbiocenosis with the displacement of representatives of the normoflora by more aggressive species. The study aims to analyze the microbiota of the oral cavity in terms of the etiopathogenesis of inflammatory periodontal diseases. The literature analysis was carried out with a depth of 20 years (from 2001 to 2021) using the following scientometric databases: PubMed, Scopus, Google Academy, Rospatent, RSCI. This article describes the role of microorganisms in the development of inflammatory diseases of periodontal tissues and provides links to 29 scientific publications. Analysis of the literature showed that, despite the species diversity of periodontopathogens, their role in the occurrence of periodontal tissue diseases has not been studied enough and requires further research.
Supporting agencies: The authors declare that there is no external funding for the exploration and analysis work
About the Author
A. V. Vinnik
Samara State Medical University
Russian Federation
Russian Federation
Anastasia V. Vinnik, Assistant of Department
Samara
References
1. Guseva N. G. Systemic scleroderma is a multidisciplinary problem // Nauchno-prakticheskaya revmatologiya = Scientific and practical rheumatology. 2011; 49 (2): 10–14. (In Russ.).
2. Martynova E. A, Makeeva I. M, Rozhnova E. V. The oral cavity as a local ecological system. Stomatologiya = Dentistry. 2008; 87(3): 68–75. (In Russ.)
3. Gordeev A. V., Galushko E. A., Savushkina N. M., Lila A. M. Periodontitis is a precursor to rheumatoid arthritis. Nauchno-prakticheskaya revmatologiya = Scientific and practical rheumatology. 2018; 56 (5): 613–621. (In Russ.).
4. Beketova T. V., Selifanova E. I. Periodontal pathology and systemic vasculitis: a look through the prism of interdisciplinary research. Nauchno-prakticheskaya revmatologiya = Scientific and practical rheumatology. 2017; 55 (6): 685–689. (In Russ.).
5. Molokov V. D., Dorzhieva Z. V. Index assessment of dental caries and periodontal diseases. Methodological guide for students. Irkutsk; 2008. 23 p. (In Russ.).
6. Tokmakova S. I., Butakova L. Yu., Efremushkin G. G. Atyasova O. V, Bondarenko O. V. Microflora of the oral mucosa in the elderly with general somatic pathology. Stomatologiya = Dentistry. 2001; 80 (4): 24–27. (In Russ.).
7. Microbiology, virology and immunology of the oral cavity. Ed. Tsarev V. N. Moscow: Geotar-media; 2013: 576 p. (In Russ.).
8. Vincent C., Agard C., Barbarot S., N'guyen J. M., Planchon B., Durant C., Pistorius M. A., Dreno B., Ponge T., Stalder J. F., Mercier J. M., Hamidou M. Orofacial manifestations of systemic sclerosis: a study of 30 consecutive patients. Revue de stomatologie et de chirurgie maxillo-faciale. 2010; 111 (3): 128–134. doi: 10.1016/j.stomax.2010.04.001.
9. Selifanova E. I., Simonova M. V. Odontogenic infection and oral dysbacteriosis in Sjogren's syndrome and disease. Dental Forum. 2009; (2): 61–65. (In Russ.).
10. Orekhova L. Yu., Zhavoronkova M. D., Suborova T. N. Modern technologies of bacteriological research of periodontal spaces]. Parodontologiya = Periodontics. 2013; 18 (2 (67)): 9–13. (In Russ.).
11. Ushakov R. V., Tsarev V. N. Antimicrobial therapy in dentistry. Principles and algorithms. Moscow: Practical medicine; 2019. 238 p. (In Russ.).
12. Chervinets V. M., Chervinets Yu. V., Leont'eva A. V., Grigor'yants E. O., Stulov N. M., Belyaev V. S. Frequency of occurrence of microbiota of various oral cavity biotopes in healthy people and patients with chronic generalized periodontitis. Materials of the International Youth Forum “Science Week 2020”. November 23-27, 2020. Stavropol : Stavropol State Medical University; 2020: 636–638. (In Russ.).
13. Mineoka T., Awano S., Rikimaru T., Kurata H., Yoshida A., Ansai T., Takehara T. Site-specific development of periodontal disease is associated with increased levels of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia in subgingival plaque. Journal of periodontology. 2008; 79 (4): 670–676. doi: 10.1902/jop.2008.070398.
14. Kil'mukhametova Yu. Kh., Batig V. M., Abramchuk I. I. Periodontal diseases against the background of somatic pathologies. Molodoy uchenyy = Young scientist. 2017; 26 (160): 57–62. (In Russ.).
15. Tsarev V. N., Nikolaeva E. N., Nosik A. S. Shcherbo S. N. Modern methods of microbiological diagnostics of periodontal tissue diseases. Meditsinskiy alfavit. Stomatologiya = Medical alphabet. Dentistry. 2005; (2): 26–29. (In Russ.).
16. Bauermeister C. D. Microbiological diagnosis of periodontal tissue diseases. Novoe v stomatologii = New in dentistry. 2003; (7): 27–30. (In Russ.).
17. Tsarev V. N., Nikolaeva E. N. Microbiological diagnostics of inflammatory diseases of the oral cavity and maxillofacial region using the domestic “Multident” system. Materials of II All-Russian Scientific and Practical Conference “Education, science and practice in Dentistry”. Moscow; 2005: 224–226. (In Russ.).
18. Tsarev V. N., Nikolaeva E. N., Maksimovskiy Yu. M. Prospects for the use of molecular genetic research methods in the diagnosis of periodontitis. Rossiyskiy stomatologicheskiy zhurnal = Russian Dental Journal. 2002; (5): 6–9. (In Russ.).
19. Bayramov G. R. The study of periodontopathogenic microflora and its etiological significance in the formation of various clinical forms of inflammatory periodontal diseases. Klinicheskaya stomatologiya = Clinical dentistry. 2010; (2): 84–86. (In Russ.).
20. Levitskii A. P., Nikolishin A. K., Stupak E. P., Skidan K. V., Levits'kii A. P., Nіkolіshin A. K., Skidan K. V. Dysbiotic aspects of pathogenesis, prevention and treatment of dental diseases. Materials of the scientific and practical conference “Innovative technologies in dentistry and clinical medicine” dedicated to the 90th anniversary of the “Ukrainian Medical Stomatological Academy” (Poltava, October 6-7, 2011). 2011; 15 (3-4): 103. (In Russ.).
21. Grigoryan A. S., Grudyanov A. I., Rabukhina N. A., Frolova O. A. Periodontal disease. Moscow: Medical information agency; 2004. 320 p. (In Russ.).
22. Ezzo P. J., Cutler C. W. Microorganisms as risk indicators for periodontal disease // Periodontology 2000. 2003; 32: 24–35.
23. Hamlet S. M., Cullinan M. P., Westerman B., Lindeman M., Bird P. S., Palmer J., Seymour G. J. Distribution of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia in an Australian population. Journal of clinical periodontology. 2001; 28 (12): 1163–1171.
24. Tsarev V. N., Nikolaeva E. N., Ippolitov E. V. Periodontal pathogenic bacteria are the main factor in the occurrence and development of periodontitis. Mikrobiologiya, epidemiologiya i immunologiya = Microbiology, Epidemiology and Immunology. 2017; (5): 102–112. (In Russ.).
25. Suda R., Kobayashi M., Nanba R., Iwamaru M., Hayashi Y., Lai C. H., Hasegawa K. Possible periodontal pathogens associated with clinical symptoms of periodontal disease in Japanise high school students. Journal of periodontology. 2004; 75 (8): 1084–1089.
26. Kopetskiy I. S., Pobozh'eva L. V., Shevelyuk Yu. V. The relationship between inflammatory periodontal diseases and general somatic diseases. Lechebnoe delo = Medical business. 2019; (2): 7–12. (In Russ.).
27. Postnikov M. A., Lyamin A. V., Tkach T. M., Vinnik A. V., Vinnik S. V. Optimization of the diagnosis of periodontal diseases when using a tool to collect the contents of the periodontal pocket for the purpose of microbiological research. Ural'skiy meditsinskiy zhurnal = Ural Medical Journal. 2020; 10 (193): 73–76. (In Russ.).
28. Vinnik A. V., Postnikov M. A., Lyamin A. V., Tkach T. M., Vinnik S. V. Improving the efficiency of diagnosing diseases of periodontal tissues using a modern research method. Aspirantskiy vestnik Povolzh'ya = Postgraduate Bulletin of the Volga Region. 2021; (1-2): 49–54. (In Russ.).
29. Makedonova Yu. A., Poroyskiy S. V., Gavrikova L. M., Afanas'eva O. Yu. The manifestation of diseases of the oral mucosa in patients who have undergone COVID-19. Vestnik Volgogradskogo gosudarstvennogo meditsinskogo universiteta = Bulletin of the Volgograd State Medical University. 2021; 1 (77): 110–115. (In Russ.).
Review
For citations:
Vinnik A.V. THE ROLE OF MICROORGANISMS IN THE DEVELOPMENT OF CHRONIC GINGIVITIS. Astrakhan medical journal. 2022;17(4):8-15. (In Russ.) https://doi.org/10.48612/agmu/2022.17.4.8.15
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