COMORBIDITY AND ITS RELATIONSHIP WITH THE COURSE OF ASTRAKHAN RICKETTSIAL FEVER
https://doi.org/10.48612/agmu/2022.17.2.54.633.1.22
Abstract
An analysis of 234 cases of Astrakhan rickettsial fever was carried out, including 69 patients with comorbidity (main group) and 165 without concomitant diseases (comparison group). It was found that comorbidity contributes to the development of a pronounced intoxication syndrome, hemorrhagic syndrome and a prolonged course of Astrakhanrickettsial fever in comparison with individuals without comorbidity. A brighter onset of Astrakhan rickettsial fever is inherent in patients with concomitant diseases of the digestive system (OR = 3,462; CI = 1,023-11,707), thrombocytopenia with pathology of the cardiovascular (OR = 4,129; CI = 1,3-13,119) and urinary system (OR = 4,817 ; CI = 1,166-19,907), a longer febrile period when combined with comorbid diseases of the respiratory (OR = 4,413; CI = 1,171-16,628) and endocrine systems (OR = 3,972; CI = 1,037-15,207), and the maximum duration of exanthema in patients with concomitant pathology of respiratory (OR = 5,0; CI = 1,326-18,654), cardiovascular (OR = 2,455; CI = 1,090-5,532), endocrine (OR = 3,750; CI = 1,129-12,459) and urinary (OR = 5,250; CI = 1,056-26,057) system.
About the Authors
K. V. Kotraleva
Astrakhan State Medical University
Russian Federation
Russian Federation
E. A. Popov
Astrakhan State Medical University
Russian Federation
Russian Federation
A. G. Serdyukov
Astrakhan State Medical University
Russian Federation
Russian Federation
E. E. Andreeva
Astrakhan State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Kotraleva K.V., Popov E.A., Serdyukov A.G., Andreeva E.E. COMORBIDITY AND ITS RELATIONSHIP WITH THE COURSE OF ASTRAKHAN RICKETTSIAL FEVER. Astrakhan medical journal. 2022;17(2):54-63. (In Russ.) https://doi.org/10.48612/agmu/2022.17.2.54.633.1.22
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