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SCIENTIFIC REVIEWS PATHOGENESIS OF IMPLANTATION FAILURES IN ENDOMETRIOSIS-ASSOCIATED INFERTILITY

https://doi.org/10.48612/agmu/2022.17.2.6.13

Abstract

Endometriosis is one of the most common and mysterious gynaecological diseases. Women with this diagnosis are twice as likely to face infertility and miscarriage. Endometriosis leads to a complex of structural and functional changes at all levels of the female reproductive system. One of the key mechanisms of infertility in endometriosis is implantation disorders, the pathogenesis of which remains completely unexplored. Still, it is known that many factors are involved in it, including chronic inflammation, resistance to progesterone, gametoand embryotoxic effects, changes in the receptivity of the endometrium and patterns of uterine contractions. It is important to know how these changes affect fertility since a complete under

About the Authors

M. R. Orazov
RUDN University
Russian Federation


S. S. Issenova
Kazakh National Medical University named after S.D. Asfendiyarov
Russian Federation


V. N. Lokshin
International Clinical Center for Reproductology “PERSONA”
Russian Federation


L. P. Ryltseva
RUDN University
Russian Federation


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Review

For citations:


Orazov M.R., Issenova S.S., Lokshin V.N., Ryltseva L.P. SCIENTIFIC REVIEWS PATHOGENESIS OF IMPLANTATION FAILURES IN ENDOMETRIOSIS-ASSOCIATED INFERTILITY. Astrakhan medical journal. 2022;17(2):6-13. (In Russ.) https://doi.org/10.48612/agmu/2022.17.2.6.13

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ISSN 1992-6499 (Print)