Blood Coagulation Parameters in Patients with Transient Ischemic Attacks
https://doi.org/10.17021/1992-6499-2026-1-51-57
Abstract
Transient ischemic attacks are short-term disturbances of cerebral circulation, often preceding the development of ischemic stroke. One of the key causes of transient ischemic attacks is increased blood clotting associated with atherosclerosis and arterial hypertension. Objective. To evaluate the parameters of the blood coagulation system in patients with transient ischemic attack, to identify the risks of thrombus formation and complications. Material and methods. The study included 160 patients with transient ischemic attack, divided into groups depending on the affected area (carotid and vertebrobasilar basins). A study of the parameters of the coagulation system was carried out: activated partial thromboplastin time, prothrombin time, fibrinogen concentration and antithrombin III activity. Results. Patients with transient ischemic attack had a significant increase in fibrinogen levels and a decrease in antithrombin III activity, indicating hypercoagulation. The most pronounced changes were found in lesions of the vertebrobasilar basin. A correlation was also found between blood pressure and the severity of changes in the hemostasis system. Conclusion. The data obtained emphasize the importance of monitoring blood coagulation parameters in patients with transient ischemic attack to reduce the risk of stroke. An individual approach to treatment, including correction of hypercoagulation, is necessary.
About the Authors
T. V. Mironenko
Moscow Medical University «Reaviz»
Russian Federation
Russian Federation
Tatyana V. Mironenko, Dr. Sci. (Med.), Professor, Professor of the Department
Moscow
S. N. Kazartseva
Lugansk City Polyclinic No. 10
Russian Federation
Russian Federation
Svetlana N. Kazartseva, Cand. Sci. (Med.), Chief Physician
Lugansk
N. N. Kochkalova
Moscow Medical University «Reaviz»
Russian Federation
Russian Federation
Natalia N. Kochkalova, student
Moscow
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For citations:
Mironenko T.V., Kazartseva S.N., Kochkalova N.N. Blood Coagulation Parameters in Patients with Transient Ischemic Attacks. Astrakhan medical journal. 2026;21(1):51-57. (In Russ.) https://doi.org/10.17021/1992-6499-2026-1-51-57
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