The Peritoneal Fluid Facies Structure in Experimental Peritonitis

Abstract

The serous cavities fluids examination, in particular, peritoneal fluid, has diagnostic importance. Biocrystallomics studies the dried droplets dry residue (facies) of biological fluids in normal conditions and in various diseases. The aim of the research was to study the peritoneal fluid solid phase structure in normal and peritonitis of various origins in an experiment on laboratory rats. Material and methods. The experiment was conducted on 125 rats, which were divided into four groups. The first group included intact animals, the second group consisted of individuals with experimental fecal peritonitis, divided into three subgroups (10, 15, and 20 % fecal suspension), the third group included urinary peritonitis, and the fourth group included chemical peritonitis. The peritoneal exudate solid phase structure was studied by wedge-shaped dehydration. Results. The facies of the peritoneal fluid of healthy animals were similar in structure, related to the conditionally radial type, and there were no pathological markers. Facies of abdominal effusion in animals with fecal and chemical peritonitis had a similar specific structure, which we called "craquelure"- facies – of the irradiated type with a multitude of three-ray, Y-shaped, cruciform cracks passing into one another. In the exudate facies structure of rats with urinary peritonitis, both common markers of intoxication processes and congestion phenomena in the form of toxic plaques, separated three-ray cracks, and special oval and rhomb-shaped inclusions were distinguished. Conclusions. The facies of the peritoneal fluid of intact animals corresponded to the facies pattern of a fluid with a small amount of protein and salts. The peritoneal fluid facies in fecal peritonitis were characterized by a "craquelure" structure consisting of three-ray cracks, contained Y-shaped cracks, and toxic plaques. The solid phase structure characteristic features of the peritoneal fluid of rats with urinary peritonitis were the irradial type of facies, the presence of separated three-ray cracks, streak cracks, rhomb-shaped and oval inclusions. The chemical peritonitis animal’s peritoneal fluid facies were similar to those of rats with fecal peritonitis.