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The value of bioimpedance analysis indicators as markers of chronic HCV infection
https://doi.org/10.17021/1992-6499-2025-3-47-52
Abstract
The combination of hepatitis C and metabolic syndrome is a predictor of a high rate of HCV infection progression. Metabolic syndrome is an unfavorable factor in the progression of the acute process in hepatitis C into chronic. Bioimpedance analysis reveals the imbalance of body composition components in patients with metabolic syndrome and chronic hepatitis C.
The purpose was to study the parameters of bioimpedance analysis in patients with acute and chronic hepatitis C and to evaluate the prognostic factors of chronization of the process in the liver.
Material and research methods. The study involved 216 patients. The device "Analyzer of assessment of the balance of water sectors of the body. Studied the nutritional status of patients and components of body composition.
Results. In patients with chronic hepatitis C, the proportion of fat mass and the ratio of waist circumference to hip circumference are significantly higher than normal (p < 0.05), as well as higher than in patients with acute hepatitis, which can be considered as a sign of the severity of the metabolic syndrome, since excess body weight obtained by increasing the volume of adipose tissue prevails.
Conclusion. Body mass index and indicators of visceral obesity (waist-to-hip ratio) are significantly increased in patients with chronic hepatitis C. The phase angle indicator can be considered as a marker of chronicity of the inflammatory process in the liver.
About the Authors
M. S. Bokhonov
Yaroslavl State Medical University
Россия
Россия
Maxim S. Bokhonov, Cand. Sci. (Med.), Associate Professor of the Department
Yaroslavl
V. L. Rozina
Yaroslavl State Medical University
Россия
Россия
Varvara L. Rosina, Cand. Sci. (Med.), Associate Professor of the Department
Yaroslavl
I. G. Sitnikov
Yaroslavl State Medical University
Россия
Россия
Ivan G. Sitnikov, Dr. Sci. (Med.), Professor, Head of the Department
Yaroslavl
A. A. Koklyushkina
Yaroslavl State Medical University
Россия
Россия
Anastasia А. Koklyushkina, Assistant of the Department
Yaroslavl
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Review
For citations:
Bokhonov M.S., Rozina V.L., Sitnikov I.G., Koklyushkina A.A. The value of bioimpedance analysis indicators as markers of chronic HCV infection. Astrakhan medical journal. 2025;20(3):47-52. (In Russ.) https://doi.org/10.17021/1992-6499-2025-3-47-52
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