A clinical example of chronic thromboembolic pulmonary hypertension in a young woman
https://doi.org/10.17021/1992-6499-2025-1-68-75
Abstract
Chronic thromboembolic pulmonary hypertension is a pathology in which obstruction of the branches of the pulmonary arteries occurs as a result of recurrent thromboembolism and secondary vasculopathy in small vessels. Without treatment, this disease can lead to insufficiency of the right ventricle and, as a result, to premature death. Surgical pulmonary artery thrombendarterectomy is the main method of choice for lesions of the main and lobar branches of the pulmonary artery. With distal lesions in the branches of the pulmonary artery, transluminal balloon angioplasty of segmental and subsegmental thromboembolic lesions of the branches of the pulmonary artery is possible. The diagnosis of chronic pulmonary embolism is extremely rare, and this is due to the difficulty of diagnosing this disease, as well as the lack of awareness among doctors about this pathology and the possibilities of its modern treatment. The presented clinical example demonstrates.
About the Authors
L. A. BiryukovaRussian Federation
Lyubov A. Biryukova, Cand. Sci. (Med.), Cardiologist
Astrakhan
O. V. Petrova
Russian Federation
Olga V. Petrova, Dr. Sci. (Med), Head of the Clinical Diagnostic Laboratory
Astrakhan
References
1. Panchenko E. P., Balakhonova T. V., Danilov N. M., Komarov A. L., Kropacheva E. S., Saidova M. A., Shakhmatova O. O., Yavelov I. S. Diagnosis and treatment of pulmonary embolism: clinical recommendations of the Eurasian Association of Cardiologists for practitioners (2021). Yevraziyskiy kardiologicheskiy zhurnal = Eurasian Journal of Cardiology. 2021; 1: 44–77 (In Russ.).
2. Petrosyan K. V., Gorbachevsky S. V., Jeblawi I. A., Sobolev A. V., Dadabaev G. M. Balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension patients with high surgical risk (four years’ experience). Russian Journal of Thoracic and Cardiovascular Surgery. 2020; 17 (4): 334–344. doi: 10.24022/0236-2791-2020-62-4-334-344.
3. Zhang M., Wang N., Zhai Z., Zhang M., Zhou R., Liu Y. Incidence and risk factors of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a systematic review and meta-analysis of cohort studies. Journal of Thoracic Disease. 2018; 17 (1): 4751–4763.
4. Willich S. N., Chuang L. H., van Hout B., Gumbs P., Jimenez D., Kroep S. Pulmonary embolism in Europe – Burden of illness in relationship to healthcare resource utilization and return to work. Thrombosis Research. 2018; 13 (1): 105–115. doi: 10.1016/j.thromres.2018.02.009.
5. Tanabe N., Kawakami T., Satoh T., Matsubara H., Nakanishi N., Ogino H. Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: A systematic review. Respiratory Investigation. 2018; 7 (1): 332–341.
6. Chazova I. E., Avdeev S. N., Tsareva N. A., Volkov A. V., Martynyuk T. V., Nakonechnikov N. N. Clinical guidelines for the diagnosis and treatment of pulmonary hypertension. Terapevticheskiy arkhiv = Therapeutic Archive. 2014; 9: 4–23 (In Russ.).
7. Danilov N. M., Matchin Yu. G., Chazova I. E. Balloon angioplasty of the pulmonary arteries in patients with incomplete chronic thromboembolic pulmonary hypertension. Consilium Medicum. 2016; 5: 59–61 (In Russ.).
8. Chazov I. E. Eurasian guidelines for the diagnosis and treatment of chronic thromboembolic pulmonary hypertension (2020). Yevraziyskiy kardiologicheskiy zhurnal = Eurasian Journal of Cardiology. 2021; 1: 6–43 (In Russ.).
9. Vasiltseva O. Ya., Edemsky A. G., Grankin D. S., Cleaver E. N., Chernyavsky A. M. The path from pulmonary embolism to chronic thromboembolic pulmonary hypertension: risk factors. Patologiya krovoobrashcheniya i kardiokhirurgiya = Circulatory pathology and cardiac surgery. 2021; 3: 11–19. doi.org/10.21688/1681-3472-2021-3-11-19 (In Russ.).
10. Demchenkova A. Yu., Veselova T. N., Martynyuk T. V., Danilov N. M., Mershin K. V., Ternovoy S. K., Chazova I. E. The state of the vascular bed, parenchyma, and pulmonary perfusion in chronic thromboembolic pulmonary hypertension according to subtraction computed tomography angiopulmonography. Kardiologiya = Cardiology. 2018; 5: 48–56. doi: org/10.18087/cardio.2018.5.10120 (In Russ.).
Supplementary files
Review
For citations:
Biryukova L.A., Petrova O.V. A clinical example of chronic thromboembolic pulmonary hypertension in a young woman. Astrakhan medical journal. 2025;20(1):68-75. (In Russ.) https://doi.org/10.17021/1992-6499-2025-1-68-75