Preview

Astrakhan medical journal

Advanced search
Open Access Open Access  Restricted Access Subscription Access

Mesenchymal tumors of the mediastinum: analysis of the clinical case

https://doi.org/10.17021/1992-6499-2025-1-76-82

Abstract

Despite the progress in diagnosis and complex treatment, the prognosis for stomach cancer remains unsatisfactory, which is explained by the frequent germination of the tumor of the entire thickness of the stomach wall with the transition to neighboring organs, as well as the presence of distant metastases. Stomach cancer with a transition to the esophagus deserves special attention, which is not allocated to a separate nosological unit, but, due to the peculiarities of the clinical course and surgical treatment, deserves to be allocated to a special group. Adequate nutrition in the perioperative period is an integral part of the management of patients undergoing surgery for malignant neoplasms of the stomach. Nutritional support for patients with stomach cancer, along with dietary recommendations, includes the appointment of additional oral, enteral and parenteral nutrition. A clinical case of the disease was considered, an effective and radical surgical treatment method was demonstrated, and perioperative nutritional support was applied, which made it possible to achieve earlier restoration of peristalsis, as well as improve the immediate results of surgical treatment by eliminating protein-energy deficiency, normalizing the metabolism of intestinal structures, preventing bacterial translocation, dystrophic and atrophic changes in the intestinal mucosa.

About the Authors

V. V. Kutukov
Astrakhan State Medical University; Regional Clinical Oncological Dispensary
Russian Federation

Vladimir V. Kutukov, Dr. Sci. (Med.), Professor, Head of the Department

Astrakhan



M. A. Gaziev
Regional Clinical Oncological Dispensary
Russian Federation

Marat A. Gaziev, Head of the Department

Astrakhan



Ya. A. Yakimenko
Astrakhan State Medical University; Regional Clinical Oncological Dispensary
Russian Federation

Yaroslavna A. Yakimenko, postgraduate student

Astrakhan



N. P. Lemeshev
Astrakhan State Medical University
Russian Federation

Nikolay P. Lemeshev, Resident

Astrakhan



A. Kh. Bukenbaev
Regional Clinical Oncological Dispensary
Russian Federation

Anvyar Kh. Bukenbaev, Oncologist

Astrakhan



K. S. Petrov
Regional Clinical Oncological Dispensary
Russian Federation

Kirill S. Petrov, Oncologist

Astrakhan



References

1. Khasanov D. Sh., Musaev M. U., Odilov D. D. Long-term results of combined treatment of patients with stage III gastric cancer. Ekonomika i sotsium = Economy and society. 2022; 11–2 (102): 761–763 (In Russ.).

2. Ibraev M. A. Cardio esophageal and gastroesophageal cancer: features of lymphogenic metastasis, principles of surgical treatment and prognostic factors. Vestnik Rossiyskogo onkologicheskogo nauchnogo tsentra imeni N. N. Blokhina RAMN = Bulletin of the Russian National Research Center N. N. Blokhina RAMS. 2015; 26 (1): 23–32 (In Russ.).

3. Besova N. S., Kalinin A. E., Nered S. N., Tryakin A. A., Gamayunov S. V., Kozlov N. A., Stilidi I. S., Karachun A. M., Kononets P. V., Malikhova O. A., Ryabov A. B., Khomyakov V. M., Fedenko A. A., Bolotina L. V., Falaleeva N. A., Nevolskikh A. A., Ivanov S. A., Khaylova Zh. V., Gevorkyan T. G., Butenko A. V., Gilmutdinova I. R., Eremushkin M. A., Ivanova G. E., Kondrateva K. O., Konchugova T. V., Krutov A. A., Obukhova O. A., Semiglazova T. Yu., Filonenko E. V., Khulamkhanova M. M., Romanov A. I. Gastric cancer. Sovremennaya onkologiya = Modern Oncology. 2021; 23 (4): 541–571 (In Russ.).

4. Prokhorov A. V., Labunets I. N., Mavrichev V. Yu., Zhilinskiy N. S. Current problems of gastroesophageal cancer surgery. Novoe v khirurgii: nauka, praktika, obuchenie = New in Surgery: Science, Practice, Training. 2021; 231–234 (In Russ.).

5. Hashimoto T., Kurokawa Y, Mori M, Doki Y. Surgical treatment of gastroesophageal junction cancer. Journal of Gastric Cancer. 2018; 18 (3): 209.

6. Bobrova O. P., Zukov R. A., Dykhno Yu. A., Modestov A. A. Gastroesophageal cancer: clinical and pathogenetic approaches to nutritional support in the perioperative period. Sibirskiy onkologicheskiy zhurnal = Siberian Journal of Oncology. 2015; 6: 91–95 (In Russ.).

7. Lidoriki I., Frountzas M., Mela E., Papaconstantinou D., Vailas M., Sotiropoulou M., Koliakos N., Toutouzas K. G., Schizas D. Postoperative changes in nutritional and functional status of gastroesophageal cancer patients. Journal of the American Nutrition Association. 2022; 41 (3): 301–309.

8. Yakimenko Ya. A., Kutukov V. V., Antonyan V. V., Gavrilova S. P., Gasanova E. R., Bogomolov D. N., Gaziev M. A. Erosive and ulcerative lesions of the mucous membrane of the stomach and duodenum during therapy with 5-fluorouracil. Uralskiy meditsinskiy zhurnal = Ural Medical Journal. 2022; 21 (6): 119–127 (In Russ.).

9. Skoropad V. Yu., Kudryavtsev D. D., Sokolov P. V., Ivanov S. A., Kaprin A. D. Features of surgical treatment of gastric cancer and esophageal-gastric junction after neoadjuvant therapy: the experience of the MRSC and a review of the literature. Sibirskiy onkologicheskiy zhurnal = Siberian Journal of Oncology. 2023; 22 (1): 101–109 (In Russ.).

10. Filippov Yu. A., Tyutyunnik V. M. Diagnosis, treatment and prevention of gastric cancer with the transition to the esophagus. Sciences of Europe. 2017; 16–1 (16): 34–38 (In Russ.).

11. Lyadov V. K., Pardabekova O. A., Lyadova M. A. Perioperative chemotherapy for stomach cancer: the state of the problem. Sovremennaya onkologiya = Modern oncology. 2018; 20 (2): 56–60 (In Russ.).

12. Chemaly R., Diab S., Khazen G., Al-Hajj G. Gastroesophageal cancer after gastric bypass surgeries: a systematic review and meta-analysis. Obesity surgery. 2022; 32 (4): 1300–1311.

13. Li G. Z., Doherty G. M., Wang J. Surgical management of gastric cancer: a review. Journal of the American Medical Association Surgery. 2022; 157 (5): 446–454.

14. Kutukov V. V., Gaziev M. A., Yakimenko Ya. A. Perioperative nutritional support for gastroesophageal cancer. Zlokachestvennye opukholi = Malignant Tumors. 2022; 12 (3S1): 113–114 (In Russ.).


Supplementary files

Review

For citations:


Kutukov V.V., Gaziev M.A., Yakimenko Ya.A., Lemeshev N.P., Bukenbaev A.Kh., Petrov K.S. Mesenchymal tumors of the mediastinum: analysis of the clinical case. Astrakhan medical journal. 2025;20(1):76-82. (In Russ.) https://doi.org/10.17021/1992-6499-2025-1-76-82

Views: 185


ISSN 1992-6499 (Print)