On the issue of blood circulation features in the fetoplacental complex in pregnant women with thyroid diseases

Abstract

Studying the issues of pregnancy management with extragenital diseases is a relevant and important task of modern obstetrics. The issue of the influence of thyroid diseases on the formation and function of the placenta remains not fully studied. Purpose of the study: to study the characteristics of the uteroplacental and fetal placental circulation in pregnant women with certain diseases of the thyroid gland. Material and research methods. 170 pregnant women were under observation. The 1st group (64 people) was formed by patients with autoimmune thyroiditis (AIT), the 2nd group (76 people) was formed by patients with diffuse toxic goiter (DTG), the 3rd (control) group was made up of 30 women with normal pregnancy. The study of feto-placental blood circulation was carried out by analyzing blood flow velocity curves (BSV) in the uterine arteries and in the umbilical cord artery. Statistical processing was carried out using the StatSoft program (Russia). The significance of the difference between the compared groups was determined using the Student's t test. Research results. An increase in indices of peripheral vascular resistance of the uterine arteries and a decrease in the systolic-diastolic ratio in the umbilical arteries in pregnant women with thyroid diseases were established, while more pronounced changes were observed in patients with autoimmune thyroiditis. Ultrasound data indicated the formation of fetoplacental insufficiency during pregnancy in women with thyroid diseases. Conclusion. To predict placental dysfunction and the formation of a risk group for the formation of perinatal complications, it is necessary to take into account the identified sonographic changes that are observed during pregnancy in patients with thyroid diseases.