Features of cytomegalovirus infection in severely premature newborns
https://doi.org/10.17021/1992-6499-2023-4-50-57
Abstract
Cytomegalovirus infection of newborns is one of the serious medical and social problems of neonatology and is often the cause of disability and mortality of the child population.
The purpose of the work was to study the incidence and clinical characteristics of cytomegalovirus infection in very premature newborns.
Materials and methods. Data from 384 medical records of premature infants with a gestational age of less than 32 weeks were analyzed.
Results. The variants of the clinical course of the disease are described, the results of laboratory studies are presented, as well as the methods of therapy used. Clinical cases with fatal outcome demonstrated. The results of the study showed that the postnatal form of the disease was 3 times more common than congenital and often occurred under the “mask” of another severe pathology, which made early diagnosis difficult. For timely diagnosis and treatment of cytomegalovirus infection in severely premature newborns, regular polymerase chain reaction examination is recommended.
Supporting agencies: The authors declare that there is no external funding for the exploration and analysis work
About the Authors
O. V. Lebedeva
Astrakhan State Medical University; Clinical Maternity Hospital named after Yu.A. Paskhalova
Russian Federation
Russian Federation
Oksana V. Lebedeva - Dr. Sci. (Med.), Associate Professor of Department, Astrakhan SMU; Deputy Chief Physician, CMH named after Yu.A. Paskhalova,
Astrakhan
N. R. Pimenova
Astrakhan State Medical University
Russian Federation
Russian Federation
Nailya R. Pimenova - Cand. Sci. (Med.), Associate Professor of Department.
Astrakhan
E. I. Kashirskaya
Astrakhan State Medical University
Russian Federation
Russian Federation
Elena I. Kashirskaya - Dr. Sci. (Med.), Associate Professor, Head of Department.
Astrakhan
T. A. Berezhnova
Regional Perinatal Center of the Alexander-Mariinsky Hospital
Russian Federation
Russian Federation
Tat'yana A. Berezhnova - Head of the Intensive Care Unit No. 2, Regional Perinatal Center.
Astrakhan
E. Z. Polyanina
Astrakhan State Medical University
Russian Federation
Russian Federation
Ella Z. Polyanina - Cand. Sci. (Med.), Associate Professor of Department.
Astrakhan
T. A. Gasanova
Clinical Maternity Hospital named after Yu.A. Paskhalova
Russian Federation
Russian Federation
Tat'yana A. Gasanova - neonatologist of the Neonatal Department.
Astrakhan
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Review
For citations:
Lebedeva O.V., Pimenova N.R., Kashirskaya E.I., Berezhnova T.A., Polyanina E.Z., Gasanova T.A. Features of cytomegalovirus infection in severely premature newborns. Astrakhan medical journal. 2023;18(4):50-57. (In Russ.) https://doi.org/10.17021/1992-6499-2023-4-50-57
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