Determination of blood parameters of laboratory rats with the formation of a regional protocol for ex-perimental studies
https://doi.org/10.29039/1992-6499-2023-2-47-54
Abstract
The paper presents the results of the study of routine blood parameters of laboratory rats in the conditions of the Astrakhan region. The aim of the work was to detect possible differences in the blood parameters of rats grown in the Astrakhan region from the values presented by the authors of other regions. As an object of study, 180 outbred rats were used, the blood of which was analyzed by 34 parameters. Small statistically significant differences were found in the blood parameters of rats in the Astrakhan region compared with laboratory animals from other regions. These differences can be associated with a number of environmental factors, namely: climatic differences, differences in atmospheric pressure, peculiarities of the composition of regional raw materials for the food base of laboratory animals.
About the Authors
O. A. Voloshan
Astrakhan State Medical University
Russian Federation
Russian Federation
O.A. Voloshan, Assistant of the Department of Biological Chemistry and Clinical Laboratory Diagnostics
Astrakhan
D. A. Gorshkov
Astrakhan State Medical University
Russian Federation
Russian Federation
D.A. Gorshkov, Cand. Sci. (Med.), Associate professor of Department
Astrakhan
O. V. Petrova
Astrakhan State Medical University; Federal Center for Cardiovascular Surgery
Russian Federation
Russian Federation
O.V. Petrova, Dr. Sci. (Med.), Professor of Department; Head of the Clinical Diagnostic Department
Astrakhan
P. A. Ivanov
Astrakhan State Medical University
Russian Federation
Russian Federation
P.A. Ivanov, Associate Professor of Department; Chief Freelance Specialist in Clinical Laboratory Diagnostics of the Ministry of Health of the Astrakhan
Astrakhan
D. M. Nikulina
Astrakhan State Medical University
Russian Federation
Russian Federation
D.M. Nikulina, Dr. Sci. (Med.), Professor, Head of Department
Astrakhan
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Review
For citations:
Voloshan O.A., Gorshkov D.A., Petrova O.V., Ivanov P.A., Nikulina D.M. Determination of blood parameters of laboratory rats with the formation of a regional protocol for ex-perimental studies. Astrakhan medical journal. 2023;18(2):47-54. (In Russ.) https://doi.org/10.29039/1992-6499-2023-2-47-54
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