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OPTIMIZATION OF APPROACHES TO PERFORMING MESOCOLONECTOMY WITH LYMPHADENECTOMY FOR TUMOR GENESIS RIGHT-SIDED COLONIC OBSTRUCTION

https://doi.org/10.17021/2021.16.1.88.97

Abstract

The combined prospective-retrospective study analyzed the results of the treatment of 157 patients operated on for obstructive intestinal obstruction due to tumours of the right colon. In the control group (81 patients), risk factors for the development of complications and “nonradicality” of surgical interventions, D2 lymphadenectomy, as well as causes that worsen the general prognosis and long-term oncological results were identified. In the main group, 76 patients underwent a developed complex diagnostic and treatment algorithm and a modified technique of laparoscopic mesocolonectomy with D3 lymph node dissection. The average number of affected lymph nodes in patients of the main group with identified metastases was 17,4 ± 4,2 compared to 10,2 ± 4,6 in patients in the control group.In both groups, the greatest number of complications was observed in patients with decompensated intestinal obstruction and multiple organ failure or a clinic of peritonitis. Intraoperative and postoperative complications in patients in the main and control groups were comparable and did not differ statistically (p > 0,05). A smaller number of anastomotic leaks in patients of the main group (n = 3; 3,9 %) compared with patients in the control group (n = 5; 6,2 %) is associated with the use of intraoperative decompression of the colon.The proposed D3 lymph node dissection technique allows increasing the number of removed lymph nodes without impairing the immediate results of patient treatment.

About the Authors

B. N. Bashankaev
GMS Clinics and Hospitals
Russian Federation


A. V. Sidorova
GMS Clinics and Hospitals
Russian Federation


B. T. Yunusov
GMS Clinics and Hospitals
Russian Federation


A. V. Arkharov
City Clinical Hospital No. 13
Russian Federation


References

1. Грошилин, В. С. Возможности ранней реабилитации пациентов и восстановления функции кишечника после общепроктологических операций / В. С. Грошилин, Д. В. Мартынов, П. В. Цыганков, В. К. Швецов, Ю. В. Лукаш // Хирургия. Журнал им. Н.И. Пирогова. - 2019. - № 12. - С. 66-73. doi: 10.17116/hirurgia201912166.

2. Грошилин, В. С. Современные аспекты профилактики осложнений после обструктивных резекций дистальных отделов толстой кишки / В. С. Грошилин, М. И. Султанмурадов, А. Н. Московченко, Н. А. Петренко // Фундаментальные исследования. - 2013. - № 9-1. - С. 24-27.

3. Давыдов, М. И. Стратегия хирургического лечения местно-распространенного рака правой половины ободочной кишки / М. И. Давыдов, Ю. И. Патютко, А. О. Расулов // Хирургия. Журнал им. Н.И. Пирогова. - 2017. - № 4. - С. 30-35.

4. Ефетов, С. К. Отдаленные результаты лечения рака правой половины ободочной кишки с применением мезоколонэктомии и Д3-лимфодиссекции / С. К. Ефетов, И. А. Тулина, А. Ю. Кравченко, Д. Н. Федоров, С. В. Ефетов, П. В. Царьков // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. - 2014. - Т. 24, № 1.- С. 62-70.

5. Филипс, Р. К. С. Колоректальная хирургия.- М. : ГЭОТАР-Медиа, 2009. - 352 с.

6. Шелыгин, Ю. А. Колопроктология : клинические рекомендации. - М. : ГЕОТАР-Медиа, 2015. - 528 с.

7. Amelung, F. J. A Population-Based Analysis of Three Treatment Modalities for Malignant Obstruction of the Proximal Colon: Acute Resection Versus Stent or Stoma as a Bridge to Surgery / F. J. Amelung, E. C. J. Consten, P. D. Siersema, P. J. Tanis // Ann. Surg. Oncol. - 2016. - Vol. 23, № 11. - P. 3660-3668. doi: 10.1245/s10434-016-5247-7.

8. Benedix, F. Comparison of 17,641 patients with right- and left-sided colon cancer: differences in epidemiology, perioperative course, histology, and survival / F. Benedix, R. Kube, F. Meyer, U.Schmidt, I.Gastinger, H.Lippert; Colon/Rectum Carcinomas (Primary Tumor) Study Group // Dis. Colon Rectum. - 2010. - Vol. 53, № 1. - P. 57-64. doi: 10.1007/DCR.0b013e3181c703a4.

9. Lee, S. D. D3 lymphadenectomy using a medial to lateral approach for curable right-sided colon cancer / S. D. Lee, S. B. Lim // Int. J. Colorectal Dis. - 2009. - Vol. 24, №3. - P. 295-300. doi: 10.1007/s00384-008-0597-7.

10. Lengele, B. Anatomical bases for the radiological delineation of lymph node areas. Upper limbs, chest and abdomen / B. Lengele, C. Nyssen-Behets, P. Scalliet // Radiother. Oncol. - 2007. - Vol. 84, № 3. - P. 335-347. doi: 10.1016/j.radonc.2007.07.016.

11. Mege, D. Surgical management of obstructive right-sided colon cancer at a national level results of a multicenter study of the French Surgical Association in 776 patients / D. Mege, G. Manceau, L. Beyer-Berjot,V. Bridoux, Z. Lakkis, A. Venara, T. Voron, F. Brunetti, I. Sielezneff, M. Karoui; AFC (French Surgical Association) Working Group // Eur. J. Surg. Oncol. - 2018. - Vol. 44, № 10. - P. 1522-1531.doi: 10.1016/j.ejso.2018.06.027.

12. Weber, K. Right hemicolectomy with central vascular ligation in colon cancer / K. Weber, W. Hohenberger // Surg. Endosc. - 2011. - Vol. 26, № 1. - P. 282. doi: 10.1007/s00464-011-1849-0.


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For citations:


Bashankaev B.N., Sidorova A.V., Yunusov B.T., Arkharov A.V. OPTIMIZATION OF APPROACHES TO PERFORMING MESOCOLONECTOMY WITH LYMPHADENECTOMY FOR TUMOR GENESIS RIGHT-SIDED COLONIC OBSTRUCTION. Astrakhan medical journal. 2021;16(1):88-97. (In Russ.) https://doi.org/10.17021/2021.16.1.88.97

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ISSN 1992-6499 (Print)