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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">astmed</journal-id><journal-title-group><journal-title xml:lang="ru">Астраханский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Astrakhan medical journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1992-6499</issn><publisher><publisher-name>ФГБОУ ВО Астраханский ГМУ Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17021/2020.15.1.84.98</article-id><article-id custom-type="elpub" pub-id-type="custom">astmed-69</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS</subject></subj-group></article-categories><title-group><article-title>АКТУАЛЬНЫЕ ВОПРОСЫ ВАКЦИНОПРОФИЛАКТИКИ ХРОНИЧЕСКОЙ ОБСТРУКТИВНОЙ БОЛЕЗНИ ЛЕГКИХ В УСЛОВИЯХ СОВРЕМЕННОЙ КЛИНИЧЕСКОЙ ПРАКТИКИ</article-title><trans-title-group xml:lang="en"><trans-title>CONTEMPORARY ISSUES IN VACCINE PROPHYLAXIS OFCHRONIC OBSTRUCTIVE PULMONARY DISEASE IN MODERN CLINICAL PRACTICE CONDITIONS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">eorlova56@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дорфман</surname><given-names>И. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Dorfman</surname><given-names>I. P.</given-names></name></name-alternatives><email xlink:type="simple">inna1977@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlov</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">orlovdoc56@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдуллаев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdullaev</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">abdullaev-musalitdin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Астраханский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ АО «Городская поликлиника № 8 им. Н.И. Пирогова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan City Clinic № 8 named after N.I. Pirogova</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2023</year></pub-date><volume>15</volume><issue>1</issue><fpage>84</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Орлова Е.А., Дорфман И.П., Орлов М.А., Абдуллаев М.А., Иванова С.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Орлова Е.А., Дорфман И.П., Орлов М.А., Абдуллаев М.А., Иванова С.В.</copyright-holder><copyright-holder xml:lang="en">Orlova E.A., Dorfman I.P., Orlov M.A., Abdullaev M.A., Ivanova S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.astmedj.ru/jour/article/view/69">https://www.astmedj.ru/jour/article/view/69</self-uri><abstract><p>Хроническая обструктивная болезнь легких занимает лидирующую позицию в структуре болезней органов дыхания по числу тяжелых осложнений с летальным исходом, инвалидности и смертности пациентов, а также значительному ущербу здоровью людей и государству в целом. Рассмотрены актуальные вопросы предупреждения обострений хронической обструктивной болезни легких с помощью вакцинопрофилактики, обсуждены подходы к применению пневмококковых вакцин для снижения риска развития внебольничной пневмонии. Приведены данные совместного применения пневмококковой и гриппозной вакцин для обеспечения стабильного течения хронической обструктивной болезни легких. Освещены доказательные основы рациональной вакцинации этой категории больных и опыт вакцинопрофилактики в рамках первичной медико-санитарной помощи населению.</p></abstract><trans-abstract xml:lang="en"><p>The chronic obstructive pulmonary disease takes a leading position among respiratory diseases, which leads to complications associated with death, disability and mortality of patients, as well as significant damage to the health of people and the general population. The article contains topical issues of chronic obstructive pulmonary diseases prevention using vaccination, discusses approaches of pneumococcal vaccines using to reduce the risk of developing community-acquired pneumonia. The materials of the article provide data on the use of pneumococcal and influenza vaccines to ensure stable chronic obstructive pulmonary disease course. This article highlights the evidence-based rational vaccination oft his patient’s category and the experience of vaccine prophylaxis in the framework of primary health care to the population.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вакцинопрофилактика</kwd><kwd>хроническая обструктивная болезнь легких</kwd><kwd>пневмококковая инфекция</kwd><kwd>пневмококковая полисахаридная 23-валентная вакцина</kwd><kwd>пневмококковая конъюгированная полисахаридная 13-валентная вакцина</kwd><kwd>внебольничная пневмония</kwd><kwd>вакцинация против гриппа</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vaccine prophylaxis</kwd><kwd>chronic obstructive pulmonary disease</kwd><kwd>pneumococcal infection</kwd><kwd>pneumococcal polysaccharide 23-valent vaccine</kwd><kwd>pneumococcal conjugated polysaccharide 13-valent vaccine</kwd><kwd>community-acquired pneumonia</kwd><kwd>influenza vaccination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гуревич, К. 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