<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">astmed</journal-id><journal-title-group><journal-title xml:lang="ru">Астраханский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Astrakhan medical journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1992-6499</issn><publisher><publisher-name>ФГБОУ ВО Астраханский ГМУ Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17021/1992-6499-2024-3-97-102</article-id><article-id custom-type="elpub" pub-id-type="custom">astmed-464</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OBSERVATIONS FROM PRACTICE</subject></subj-group></article-categories><title-group><article-title>Мезенхимальные опухоли средостения: разбор клинического случая</article-title><trans-title-group xml:lang="en"><trans-title>Mesenchymal tumors of the mediastinum: analysis of the clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8167-2997</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кутуков</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutukov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кутуков Владимир Владимирович - доктор медицинских наук, профессор, заведующий кафедрой онкологии и лучевой терапии.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Vladimir V. Kutukov - Dr. Sci. (Med.), Professor, Head of the Department, Astrakhan State Medical University.</p><p>Astrakhan</p></bio><email xlink:type="simple">kutukov2006@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8780-4428</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Газиев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaziev</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Газиев Марат Алилович - заведующий торакальным отделением.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Marat A. Gaziev - Head of the Department, Regional Clinical Oncological Dispensary.</p><p>Astrakhan</p></bio><email xlink:type="simple">marat10_1@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2276-2562</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якименко</surname><given-names>Я. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakimenko</surname><given-names>Ya. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якименко Ярославна Александровна - аспирант кафедры онкологии и лучевой терапии, АГМУ.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Yaroslavna A Yakimenko - postgraduate student, Astrakhan State Medical University.</p><p>Astrakhan</p></bio><email xlink:type="simple">maleeva.yaroslavna@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-8707-5453</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лемешев</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Lemeshev</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лемешев Николай Петрович - клинический ординатор кафедры онкологии и лучевой терапии.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Nikolay P. Lemeshev - Clinical Resident, Astrakhan State Medical University.</p><p>Astrakhan</p></bio><email xlink:type="simple">nikolaslem20@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-1762-6606</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Букенбаев</surname><given-names>А. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Bukenbaev</surname><given-names>A. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Букенбаев Анвяр Хасаинович - врач-онколог торакального отделения.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Anvyar Kh. Bukenbaev - Oncologist, Regional Clinical Oncological Dispensary.</p><p>Astrakhan</p></bio><email xlink:type="simple">anvyr1982@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-8769-5552</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петров Кирилл Сергеевич - врач-онколог торакального отделения.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Kirill S. Petrov - Oncologist, Regional Clinical Oncological Dispensary.</p><p>Astrakhan</p></bio><email xlink:type="simple">kir.petrov86@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Астраханский государственный медицинский университет; Областной клинический онкологический диспансер</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan State Medical University; Regional Clinical Oncological Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Областной клинический онкологический диспансер</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Oncological Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Астраханский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>19</day><month>10</month><year>2024</year></pub-date><volume>19</volume><issue>3</issue><fpage>97</fpage><lpage>102</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кутуков В.В., Газиев М.А., Якименко Я.А., Лемешев Н.П., Букенбаев А.Х., Петров К.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Кутуков В.В., Газиев М.А., Якименко Я.А., Лемешев Н.П., Букенбаев А.Х., Петров К.С.</copyright-holder><copyright-holder xml:lang="en">Kutukov V.V., Gaziev M.A., Yakimenko Y.A., Lemeshev N.P., Bukenbaev A.K., Petrov K.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.astmedj.ru/jour/article/view/464">https://www.astmedj.ru/jour/article/view/464</self-uri><abstract><p>Опухоли средостения включают в себя широкий спектр доброкачественных и злокачественных новообразований. Последние на ранних этапах характеризуются длительным скрытым течением и несут значительную угрозу сдавления и/или инвазии жизненно важных органов средостения. Сложность их диагностики дополняет смешанная клиническая картина, схожая с другими соматическими заболеваниями. С учетом перечисленного опухоли средостения являются актуальной проблемой для современного онкологического сообщества, требую т совершенствования знаний и накопления опыта по их хирургическому и консервативному лечению. Мезенхимальные опухоли средостения составляют малую часть опухолей медиастинального пространства, а низкая заболеваемость новообразованиями данной анатомической локализации диктует необходимость междисциплинарного подхода к вопросам диагностики и лечения. Рассмотрен клинический случай заболевания, продемонстрирован эффективный и радикальный хирургический метод лечения. Бессимптомное течение ранних стадий заболевания, а также относительно малая эффективность оперативного вмешательства в позднем периоде онкогенеза диктует необходимость поиска новых подходов в диагностике и лечении опухолей средостения.</p></abstract><trans-abstract xml:lang="en"><p>Mediastinal tumors include a wide range of benign and malignant neoplasms. The latter in the early stages are characterized by a long latent course and carry a significant threat of com pression and / or invasion of vital organs of the mediastinum. The complexity of their diagnosis is complemented by a mixed clinical picture, similar to other somatic diseases. Considering all of the above, mediastinal tumors are an urgent problem for the modem oncological community, they require improving knowledge and gaining experience in their surgical and conservative treatment. Mesenchym al tumors of the mediastinum make up a small part of tumors of the mediastinal space, and the low incidence of neoplasm s of this anatomical localization dictates the need for an interdisciplinary approach to the diagnosis and treatment of mesenchym al tumors of the mediastinal space. A clinical case of the disease is considered, an effective and radical surgical treatment method is demonstrated. The asymptomatic course of the early stages of the disease, as w ell as the relatively low effectiveness of surgical intervention in the late period of oncogenesis, dictates the need to search for new approaches in the diagnosis and treatment of mediastinal tumors.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>новообразования средостения</kwd><kwd>мезенхимальные опухоли</kwd><kwd>опухоли медиастинального пространства</kwd></kwd-group><kwd-group xml:lang="en"><kwd>neoplasms of the mediastinum</kwd><kwd>mesenchymal tumors</kwd><kwd>tumors of the mediastinal space</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Колбанов К. И. и др. Опухоли средостения: классификации // Онкология. Журнал имени П. А. Герцена. 2019. Т. 8, № 6. С. 471-478.</mixed-citation><mixed-citation xml:lang="en">Kolbanov K. I. et al. Mediastinal tumors: classification. Onkologiya. Zhurnal imeni P. A. Gertsena = Oncology. The Journal named after P. A. Herzen. 2019; 8 (6): 471-478 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Потешкина Н. Г. и др. Образования средостения в клинической практике // Медицинский совет. 2018. № 5. С. 104-108.</mixed-citation><mixed-citation xml:lang="en">Poteshkina N. G. et al. Mediastinal neoplasms in clinical practice. Meditsinskiy sovet = Medical Council. 2018; 5: 104-108 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Давыдов М. М., Мачаладзе З. О. Саркомы торакоабдоминальной локализации (современная стратегия хирургического лечения) // Вестник Российского онкологического научного центра имени Н. Н. Блохина РАМН. 2015. Т. 26, № 1. С. 3-14.</mixed-citation><mixed-citation xml:lang="en">Davydov M. M., Machaladze Z. O. Thoracoabdominal sarcomas (modern strategy of surgical treatment). Vestnik RONTs im. N. N. Blokhina RAMN = Journal of N. N. Blokhin Russian Cancer Research Center RAMS. 2015; 26 (1): 3 -14 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Alothaimeen H. S., Memon M. A. Treatment outcome and prognostic factors of malignant thymoma-a single institution experience // Asian Pacific Journal of Cancer Prevention. 2020. Vol. 21, no. 3. P. 653. doi: 10.31557/APJCP.2020.21.3.653.</mixed-citation><mixed-citation xml:lang="en">Alothaimeen H. S., Memon M. A. Treatment outcome and prognostic factors of malignant thymoma-a single institution experience. Asian Pacific Journal of Cancer Prevention: APJCP. 2020; 21 (3): 653. doi: 10.31557/APJCP.2020.21.3.653.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Пысанова Ж. У. Хирургическое лечение при доброкачественных и злокачественных опухолях грудной стенки // Онкология и радиология Казахстана. 2019. № S. С. 67-68.</mixed-citation><mixed-citation xml:lang="en">Pysanova Zh. U. Surgical treatment for benign and malignant tumors of the chest wall. Onkologiya i radiologiya Kazakhstana = Oncology and Radiology of Kazakhstan. 2019; S: 67 -68 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">da Mota Gomes M. Hermann Oppenheim, a pioneer of modern German neurology // Revista brasileira de neurologia. 2019. Vol. 55. P. 36-40.</mixed-citation><mixed-citation xml:lang="en">da Mota Gomes M. Hermann Oppenheim, a pioneer of modern German neurology. Revista brasileira de neurologia = Brazilian Journal of Neurology . 2019; 55: 36-40.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Baram A., Tayeb Z. A. Mediastinal Masses: Retrospective single center based study // Journal of Cancer Science and Therapy. 2016. Vol. 8, no. 10. P. 252-256. doi: 10.4172/1948-5956.1000422.</mixed-citation><mixed-citation xml:lang="en">Baram A., Tayeb Z. A. Mediastinal Masses: Retrospective single center based study. Journal of Cancer Science and Therapy. 2016; 8 (10): 252-256. doi: 10.4172/1948-5956.1000422.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Dixit R. et al. Diagnostic evaluation of mediastinal lesions: Analysis of 144 cases // Lung India. 2017. Vol. 34, no. 4. P. 341-348. doi: 10.4103/lungindia.lungindia_311_16.</mixed-citation><mixed-citation xml:lang="en">Dixit R. et al. Diagnostic evaluation of mediastinal lesions: Analysis of 144 cases. Lung India. 2017; 34 (4): 341-348. doi: 10.4103/lungindia.lungindia_311_16.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Рябов А. Б. и др. Клинический алгоритм диагностики и лечения опухолей средостения // Хирургия. Журнал имени Н. И. Пирогова. 2022. № 5. С. 43-51.</mixed-citation><mixed-citation xml:lang="en">Ryabov A. B. et al. Clinical algorithm for the diagnosis and treatment of mediastinal tumors. Khirurgiya. Zhurnal imtni N. I. Pirogova = Surgery. The Journal named after N. I. Pirogov. 2022; 5: 43-51 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Новиков Д. В. и др. Хирургическое лечение местнораспространенной ангиосаркомы переднего средостения. Клинический случай // Современная онкология. 2022. Т. 24, № 3. С. 336-339.</mixed-citation><mixed-citation xml:lang="en">Novikov D. Vet al. Surgical treatment of locally advanced anterior mediastinal angiosarcoma. A clinical case. Sovremennaya onkologiya = Modern Oncology. 2022; 24 (3): 336-339 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Шевченко Ю. Л. и др. Современные технологии в хирургии средостения // Вестник Национального медико-хирургического центра имени Н. И. Пирогова. 2020. Т. 15, № 1. С. 4-12. doi: 10.25881/BPNMSC.2020.82.77.001.</mixed-citation><mixed-citation xml:lang="en">Shevchenko Yu. L. et al. Modern technologies in mediastinal surgery. Vestnik Natsionalnogo mediko-khirurgicheskogo tsentra imeni N. I. Pirogova = Bulletin of the National Medico-Surgical Center named after N. I. Pirogov. 2020; 15 (1) (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Grisbolaki E. et al. A short history of mediastinal tumours // Kardiochirurgia i Torakochirurgia Polska / Polish Journal of Thoracic and Cardiovascular Surgery. 2023. Vol. 20, no. 3. P. 187-192.</mixed-citation><mixed-citation xml:lang="en">Grisbolaki E. et al. A short history of mediastinal tumours. Kardiochirurgia i Torakochirurgia Polska / Polish Journal of Thoracic and Cardiovascular Surgery. 2023; 20 (3): 187-192.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Топольницкий Е. Б., Бородина Ю. А. Видеоторакоскопические вмешательства при опухолях и кистах средостения // Эндоскопическая хирургия. 2020. Т. 26, № 6. С. 17-21.</mixed-citation><mixed-citation xml:lang="en">Topol’nitskiy E. B., Borodina Yu. A. Videothoracoscopic interventions for tumors and cysts of the mediastinum. Endoskopicheskaya khirurgiya = Endoscopic surgery. 2020; 26 (6): 17-21 (In Russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
