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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">astmed</journal-id><journal-title-group><journal-title xml:lang="ru">Астраханский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Astrakhan medical journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1992-6499</issn><publisher><publisher-name>ФГБОУ ВО Астраханский ГМУ Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17021/2019.14.3.115.121</article-id><article-id custom-type="elpub" pub-id-type="custom">astmed-43</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ASSISTANCE TO THE PRACTITIONER</subject></subj-group></article-categories><title-group><article-title></article-title><trans-title-group xml:lang="en"><trans-title>THE RESULTS OF TREATMENT OF ALLERGIC DERMATOSIS ASSOCIATED WITH INTESTINAL PARASITOSES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Hasanova</surname><given-names>V. L.</given-names></name></name-alternatives><email xlink:type="simple">h.vafa@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="en" id="aff-1"><institution>Azerbaijan Medical University; Baku Dispensary No. 1 of Skin and Venereal Diseases, The Ministry of Healthcare of Azerbaijan Republic</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>27</day><month>02</month><year>2023</year></pub-date><volume>14</volume><issue>3</issue><fpage>115</fpage><lpage>121</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Hasanova V.L., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Hasanova V.L.</copyright-holder><copyright-holder xml:lang="en">Hasanova V.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.astmedj.ru/jour/article/view/43">https://www.astmedj.ru/jour/article/view/43</self-uri><trans-abstract xml:lang="en"><p>The article presents information on the results of the treatment of allergic dermatosis associated with intestinal parasitoses against the background of normal intestinal microflora and against the background of dysbacteriosis. The intestinal microflora was studied in 73 patients with only allergic dermatosis and 108 patients with allergic dermatosis associated with intestinal parasitoses before and after the treatment. General and biochemical testsof blood, urine, and feces of these patients were performed using generally accepted laboratory research methods. In order to clarify the role of intestinal parasitoses in the clinical course of allergic dermatoses associated with intestinal parasitoses and assess their impact on the treatment, the patients were divided into 2 treatment groups. Group I - 63 patients with allergic dermatosis associated with intestinal parasitoses were treated comprehensively for both pathologies; Group II -45 patients with allergic dermatosis associated with intestinal parasitoses were treated only for allergic dermatoses. The results of the study showed that after treatment of allergic dermatoses associated with intestinal parasitoses against the background of normal microflora, there was a decrease in clinical signs by 3-4 times, and against the background of dysbacteriosis - by 2 times. It was also revealed that the effectiveness of complex treatment of allergic dermatoses associated with intestinal parasitoses (70,80 ± 5,59 %) is significantly higher than the effectiveness of treatment only for allergic dermatoses (27,91 ± 6,79 %).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>allergic dermatosis</kwd><kwd>atopic dermatitis</kwd><kwd>urticaria</kwd><kwd>eczema</kwd><kwd>acne vulgaris</kwd><kwd>intestinal parasitoses</kwd><kwd>complex treatment</kwd><kwd>clinical signs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kungurov N. V., Zilberberg N. V., Kokhan M. M., Voronova O. A., Evstigneeva N. P., Kharsevich E. L., Polishchuk A. I. Razrabotka novogo sredstva topicheskoy proaktivnoy terapii dlya bol'nykh khronicheskimi dermatozami [Design of a new agent for topical proactive therapy in patients with chronic dermatoses]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2013, vol. 11, no. 6, pp. 76-81.</mixed-citation><mixed-citation xml:lang="en">Kungurov N. V., Zilberberg N. V., Kokhan M. M., Voronova O. A., Evstigneeva N. P., Kharsevich E. L., Polishchuk A. I. Razrabotka novogo sredstva topicheskoy proaktivnoy terapii dlya bol'nykh khronicheskimi dermatozami [Design of a new agent for topical proactive therapy in patients with chronic dermatoses]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2013, vol. 11, no. 6, pp. 76-81.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Lavrov A. A., Nevozinskaya Z. A., SorkinaI. L., Korsunskaya I. M. Vozmozhnosti kliokhinola v terapii dermatozov, oslozhnennykh vtorichnoy infektsiyey [The abilities of clioquinol in the therapy of dermatoses complicated by secondary infection]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2013, vol. 11, no. 6, pp. 108-111.</mixed-citation><mixed-citation xml:lang="en">Lavrov A. A., Nevozinskaya Z. A., SorkinaI. L., Korsunskaya I. M. Vozmozhnosti kliokhinola v terapii dermatozov, oslozhnennykh vtorichnoy infektsiyey [The abilities of clioquinol in the therapy of dermatoses complicated by secondary infection]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2013, vol. 11, no. 6, pp. 108-111.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Masyukova S. A., Mordovtseva V. V., Kakhishvili N. N., Sanakoeva E. G., Kruglova L. S., Sokolova Yu. P. Lecheniye akne nizkimi dozami izotretionina [Low-dose isotretinoin treatment of acne]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2013, vol. 11, no. 6, pp. 7-12.</mixed-citation><mixed-citation xml:lang="en">Masyukova S. A., Mordovtseva V. V., Kakhishvili N. N., Sanakoeva E. G., Kruglova L. S., Sokolova Yu. P. Lecheniye akne nizkimi dozami izotretionina [Low-dose isotretinoin treatment of acne]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2013, vol. 11, no. 6, pp. 7-12.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Matushevskaya E. V., Svirshevskaya E. V. Antigistaminnyye preparaty v dermatologii [Antihistamines in dermatology]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2018, vol. 17, no. 1, pp. 14-21.</mixed-citation><mixed-citation xml:lang="en">Matushevskaya E. V., Svirshevskaya E. V. Antigistaminnyye preparaty v dermatologii [Antihistamines in dermatology]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2018, vol. 17, no. 1, pp. 14-21.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Monakhov S. A. Rasshirennyye vozmozhnosti v terapii akne s primeneniyem tsink-eritromitsinovogo kompleksa [Advanced options in the treatment of acne using zinc-erythromycin complex]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2017, vol. 16, no. 5, pp. 49-57.</mixed-citation><mixed-citation xml:lang="en">Monakhov S. A. Rasshirennyye vozmozhnosti v terapii akne s primeneniyem tsink-eritromitsinovogo kompleksa [Advanced options in the treatment of acne using zinc-erythromycin complex]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2017, vol. 16, no. 5, pp. 49-57.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Proshutinskaya D. V., Skripkina P. A. Nummulyarnaya ekzema u detey i vzroslykh: klinicheskaya kartina i differentsirovannyy podkhod k terapii [Nummular eczema in children and adults: clinical picture and differential therapy approaches]. Vestnik dermatologii i venerologii [Journal of Dermatology and Venereology], 2015, no. 6, pp. 85-88.</mixed-citation><mixed-citation xml:lang="en">Proshutinskaya D. V., Skripkina P. A. Nummulyarnaya ekzema u detey i vzroslykh: klinicheskaya kartina i differentsirovannyy podkhod k terapii [Nummular eczema in children and adults: clinical picture and differential therapy approaches]. Vestnik dermatologii i venerologii [Journal of Dermatology and Venereology], 2015, no. 6, pp. 85-88.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Svirshevskaya E. V., Matushevskaya E. V., Chudakov D. B., Matushevskaya Yu. I. Rol' infektsii v patogeneze allergodermatozov [The role of infection in the pathogenesis of allergodermatoses]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2015, vol. 14, no. 2, pp. 4-10.</mixed-citation><mixed-citation xml:lang="en">Svirshevskaya E. V., Matushevskaya E. V., Chudakov D. B., Matushevskaya Yu. I. Rol' infektsii v patogeneze allergodermatozov [The role of infection in the pathogenesis of allergodermatoses]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2015, vol. 14, no. 2, pp. 4-10.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Silina L. V., Hardikova S. A., Kolbina M. S., Koryukina E. B., Kashcheeva Ya. V. Proaktivnaya terapiya atopicheskogo dermatita [Proactive therapy of atopic dermatitis]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2017, vol. 16, no. 6, pp. 96-99.</mixed-citation><mixed-citation xml:lang="en">Silina L. V., Hardikova S. A., Kolbina M. S., Koryukina E. B., Kashcheeva Ya. V. Proaktivnaya terapiya atopicheskogo dermatita [Proactive therapy of atopic dermatitis]. Klinicheskaya dermatologiya i venerologiya [Clinical Dermatology and Venereology], 2017, vol. 16, no. 6, pp. 96-99.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Tlish M. M., Gluzmin M. I., Kartashevskaya M. I., Psavok F. A. Atopicheskiy dermatit u detey: perspektivy primeneniya innovatsionnykh sredstv v naruzhnoyterapii [Atopic dermatitis in children: prospects of using innovationproducts as an external therapy]. Vestnik dermatologii i venerologii [Journal of Dermatology and Venereology], 2016, no. 2, рр. 96-102.</mixed-citation><mixed-citation xml:lang="en">Tlish M. M., Gluzmin M. I., Kartashevskaya M. I., Psavok F. A. Atopicheskiy dermatit u detey: perspektivy primeneniya innovatsionnykh sredstv v naruzhnoyterapii [Atopic dermatitis in children: prospects of using innovationproducts as an external therapy]. Vestnik dermatologii i venerologii [Journal of Dermatology and Venereology], 2016, no. 2, рр. 96-102.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Dahnhardt-Pfeiffer S., Dahnhardt D., Buchner M., Walter K., Proksch E., Folster-Holst R. Comparison of effects of tacrolimus ointment and mometasone furoate cream on the epidermal barrier of patients with atopic dermatitis. J. Dtch. Dermatol. Ges., 2013, vol. 11, no. 5, pp. 437-443. doi: 10.1111/ddg.12074.</mixed-citation><mixed-citation xml:lang="en">Dahnhardt-Pfeiffer S., Dahnhardt D., Buchner M., Walter K., Proksch E., Folster-Holst R. Comparison of effects of tacrolimus ointment and mometasone furoate cream on the epidermal barrier of patients with atopic dermatitis. J. Dtch. Dermatol. Ges., 2013, vol. 11, no. 5, pp. 437-443. doi: 10.1111/ddg.12074.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Del Rosso J. Q. Azelaic acid topical formulations: differentiation of 15 % gel and 15 % foam. J. Clin. Aesthet Dermatol., 2017, vol. 10, no. 3, pp. 37-40.</mixed-citation><mixed-citation xml:lang="en">Del Rosso J. Q. Azelaic acid topical formulations: differentiation of 15 % gel and 15 % foam. J. Clin. Aesthet Dermatol., 2017, vol. 10, no. 3, pp. 37-40.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ibler K. S., Jemec G. B. Novel investigational therapies for atopic dermatitis. Expert Opin. Investig. Drugs, 2015, vol. 24, no. 1, pp. 61-68. doi: 10.1517/13543784.2015.957756.</mixed-citation><mixed-citation xml:lang="en">Ibler K. S., Jemec G. B. Novel investigational therapies for atopic dermatitis. Expert Opin. Investig. Drugs, 2015, vol. 24, no. 1, pp. 61-68. doi: 10.1517/13543784.2015.957756.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Mrowietz U. Cyclosporine as maintenance therapy in patients with severe psoriasis. J.Am. Acad. Dermatol., 2013, vol. 69, no. 2, pp. 308-309. doi: 10.1016/j.joad, 2012, 09.005.</mixed-citation><mixed-citation xml:lang="en">Mrowietz U. Cyclosporine as maintenance therapy in patients with severe psoriasis. J.Am. Acad. Dermatol., 2013, vol. 69, no. 2, pp. 308-309. doi: 10.1016/j.joad, 2012, 09.005.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Sigurgeirsson B.,Boznanski A., Todd G., Vertruyen A., Schuttelaar M. L., Zhu X., Schauer U., Qaqundah P., Poulin Y., Kristjansson S., von Berg A., Nieto A., Boguniewicz M., Paller A. S., Dakovic R., Ring J., Luger T. Safety and efficacy of pimecrolimus in atopic dermatitis: a 5-year randomized trial. Pediatrics, 2015, vol. 135, pp. 597-606. doi: 10.1542/peds.2014-1990.</mixed-citation><mixed-citation xml:lang="en">Sigurgeirsson B.,Boznanski A., Todd G., Vertruyen A., Schuttelaar M. L., Zhu X., Schauer U., Qaqundah P., Poulin Y., Kristjansson S., von Berg A., Nieto A., Boguniewicz M., Paller A. S., Dakovic R., Ring J., Luger T. Safety and efficacy of pimecrolimus in atopic dermatitis: a 5-year randomized trial. Pediatrics, 2015, vol. 135, pp. 597-606. doi: 10.1542/peds.2014-1990.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Zuo W. X., Li X. Y., Cai G. Y., Chen Y. Q. A randomized single-blind controlled clinical trial of taсrolimus mouth rinse on erosive oral lichen planus. Shanghai Kou Qiang Yi Xue, 2013, vol. 22, issue 6, pp. 708-710.</mixed-citation><mixed-citation xml:lang="en">Zuo W. X., Li X. Y., Cai G. Y., Chen Y. Q. A randomized single-blind controlled clinical trial of taсrolimus mouth rinse on erosive oral lichen planus. Shanghai Kou Qiang Yi Xue, 2013, vol. 22, issue 6, pp. 708-710.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
