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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">astmed</journal-id><journal-title-group><journal-title xml:lang="ru">Астраханский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Astrakhan medical journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1992-6499</issn><publisher><publisher-name>ФГБОУ ВО Астраханский ГМУ Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17021/1992-6499-2024-1-85-92</article-id><article-id custom-type="elpub" pub-id-type="custom">astmed-401</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Клинико-гематологическая характеристика и осложнения больных хроническим лимфолейкозом в Астраханской области</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and hematological characteristics and complications of patients with chronic lymphocytic leukemia in the astrakhan region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козак</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozak</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козак Дарья Михайловна, ассистент кафедры факультетской терапии и профессиональных болезней с курсом последипломного образования</p><p>г. Астрахань</p></bio><bio xml:lang="en"><p>Dar’ya M. Kozak, Assistant, Astrakhan State Medical University; General Practitioner, New Polyclinic – Astrakhan</p><p>Astrakhan</p></bio><email xlink:type="simple">kodami10@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овсянникова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovsyannikova</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Овсянникова Елена Георгиевна, доктор медицинских наук, заведующий кафедрой профилактической медицины и здорового образа жизни</p><p>г. Астрахань</p></bio><bio xml:lang="en"><p>Elena G. Ovsyannikova, Dr. Sci. (Med.), Head of the Department</p><p>Astrakhan</p></bio><email xlink:type="simple">elenaagma@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Астраханский государственный медицинский университет; ОАО «Новая Поликлиника – Астрахань»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan State Medical University; New Polyclinic – Astrakhan</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Астраханский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>11</day><month>04</month><year>2024</year></pub-date><volume>19</volume><issue>1</issue><fpage>85</fpage><lpage>92</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Козак Д.М., Овсянникова Е.Г., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Козак Д.М., Овсянникова Е.Г.</copyright-holder><copyright-holder xml:lang="en">Kozak D.M., Ovsyannikova E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.astmedj.ru/jour/article/view/401">https://www.astmedj.ru/jour/article/view/401</self-uri><abstract><p>Изучена заболеваемость хроническим лимфолейкозом в Астраханской области. Выявлена закономерность развития инфекционных осложнений хронического лимфолейкоза в зависимости от пола, возраста больных, вида возбудителей бактериальной, вирусной и грибковой этиологии. Исследованы инфекционные осложнения хронического лимфолейкоза в зависимости от локализации процесса, и стадии течения основного заболевания.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the incidence of chronic lymphocytic leukemia in the Astrakhan region. The regularity of the development of infectious complications of chronic lymphocytic leukemia depending on the gender, age of patients, type of pathogens of bacterial, viral and fungal etiology was revealed. Infectious complications of chronic lymphocytic leukemia have been studied depending on the localization of the process and the stage of the course of the underlying disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический лимфолейкоз</kwd><kwd>инфекционные осложнения</kwd><kwd>возбудители бактериальной</kwd><kwd>вирусной и грибковой этиологии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic lymphocytic leukemia</kwd><kwd>infectious complications</kwd><kwd>pathogens of bacterial</kwd><kwd>viral and fungal etiology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аглямова Т. А., Хаертымова Р. Т. Популяционные аспекты эпидемиологии герпесвирусных инфекций в крупном промышленном городе // Практическая медицина. 2017. № 4 (105). С. 56–62.</mixed-citation><mixed-citation xml:lang="en">Aglyamova T. A., Khaertymova R. T. Population aspects of epidemiology of herpesvirus infections in a large industrial city. Prakticheskaya meditsina = Practical medicine. 2017; 4(105): 56–62.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бондарева И. Б., Сергиенко В. И. Математическая статистика в клинических исследованиях. М.: ГЭОТАР-Медиа, 2006. С. 156–160.</mixed-citation><mixed-citation xml:lang="en">Bondareva I. B., Sergienko V. I. Matematicheskaya statistika v klinicheskikh issledovaniyakh = Mathematical statistics in clinical research. Moscow: GEOTAR-Media; 2006. P. 156–160.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Волкова М. А. Клиническая онкогематология. М.: Медицина, 2007. С. 396-405.</mixed-citation><mixed-citation xml:lang="en">Volkova M. A. Klinicheskaya onkogematologiya = Clinical oncohematology, a guide for doctors. 2 nd ed. Moscow: Meditsina; 2007: 396–405.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Чеботкевич В. Н. Ассоциации цитомегаловирусных и респираторных вирусных инфекций у больных различными формами лейкозов // Трасфузиология. 1998 г. Т. 16, № 28. С. 156–159.</mixed-citation><mixed-citation xml:lang="en">Chebotkevich V. N. Associations of cytomegalovirus and respiratory viral infections in patients with various forms of leukemia. Transfusiologiya = Transfusiology. 1998; 16(28): 156–159.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Berger C. Infectious mononucleosis // Therapeutische Umschau. 2003. Vol. 60, № 10. P. 625–630.</mixed-citation><mixed-citation xml:lang="en">Berger C. Infectious mononucleosis. Therapeutische Umschau. 2003. 60(10): 625–630.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Boeckh M., Nichols W. G., Papanicolaou G. Cytomegalovirus in hematopoietic stem cell transplant recipients : current status, known challenges, and future strategies // Blood and Marrow Transplantation. 2003. № 9. Р. 543–558.</mixed-citation><mixed-citation xml:lang="en">Boeckh M., Nichols W. G., Papanicolaou G. Cytomegalovirus in hematopoietic stem cell transplant recipients: current status, known challenges, and future strategies. Biol Blood Marrow Transplant. 2003; 9: 543–558.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Dignani M. C. Epidemiology of invasive fungal diseases on the basis of autopsy reports // F1000Prime Reports. 2014. Vol. 81, № 6. Р. 25–27. doi: 10.12703/P6-81.</mixed-citation><mixed-citation xml:lang="en">Dignani M. C. Epidemiology of invasive fungal diseases on the basis of autopsy reports. F1000Prime Reports. 2014; 81(6): 25–27. doi: 10.12703/P6-81.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Elter T. Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab // Annals of Hematology. 2009. Vol. 88, № 2. P. 121–132.</mixed-citation><mixed-citation xml:lang="en">Elter T. Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab. Annals of Hematology. 2009; 88(2): 121–132.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Linet M. S. Chronic lymphocytic leukaemia : an overview of etiology in light of recent developments in classification and pathogenesis // British Journal of Haematology. 2017. Vol. 139. P. 672–686.</mixed-citation><mixed-citation xml:lang="en">Linet M. S. Chronic lymphocytic leukaemia: an overview of etiology in light of recent developments in classification and pathogenesis. British Journal of Haematology. 2017; 139: 672–686.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Yadegarynia D. Pneumonitis due to cytomegalovirus in an immunocompromised patient // Iranian Journal of Clinical Infectious Disease. 2009. Vol. 4, № 4. P. 238–240.</mixed-citation><mixed-citation xml:lang="en">Yadegarynia D. Pneumonitis due to cytomegalovirus in an immunocompromised patient. Iranian Journal of Clinical Infectious Disease. 2009; 4(4): 238–240.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
