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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">astmed</journal-id><journal-title-group><journal-title xml:lang="ru">Астраханский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Astrakhan medical journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1992-6499</issn><publisher><publisher-name>ФГБОУ ВО Астраханский ГМУ Минздрава России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29039/1992-6499-2023-2-110-119</article-id><article-id custom-type="elpub" pub-id-type="custom">astmed-278</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OBSERVATIONS FROM PRACTICE</subject></subj-group></article-categories><title-group><article-title>О трудностях диагностики и осложнениях опухоли Клацкина</article-title><trans-title-group xml:lang="en"><trans-title>About the difficuties of the diagnostics and treament of the Klatskin`s tumour</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дедов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dedov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>А.В. Дедов, кандидат медицинских наук, доцент, доцент кафедры пропедевтики внутренних болезней</p><p>Астрахань</p></bio><bio xml:lang="en"><p>A.V. Dedov, Cand. Sci (Med.), Associate Professor, Associate Professor of Department</p><p>Astrakhan</p></bio><email xlink:type="simple">dedov1965.d@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мустафин</surname><given-names>Р. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Mustafin</surname><given-names>R. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Р.Д. Мустафин, доктор медицинских наук, профессор, заведующий кафедрой госпитальной хирургии</p><p>Астрахань</p></bio><bio xml:lang="en"><p>R.D. Mustafin, Dr. Sci (Med.), Professor, Head of the Department</p><p>Astrakhan</p></bio><email xlink:type="simple">robert-mustafin1@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полухина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Polukhina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Е.А. Полухина, студентка III курса лечебного факультета</p><p>Астрахань</p></bio><bio xml:lang="en"><p>E.A. Polukhina, 3rd year student of the Faculty of Medicine</p><p>Astrakhan</p></bio><email xlink:type="simple">katena-polukhina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Астраханский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>18</day><month>07</month><year>2023</year></pub-date><volume>18</volume><issue>2</issue><elocation-id>110–119</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Дедов А.В., Мустафин Р.Д., Полухина Е.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Дедов А.В., Мустафин Р.Д., Полухина Е.А.</copyright-holder><copyright-holder xml:lang="en">Dedov A.V., Mustafin R.D., Polukhina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.astmedj.ru/jour/article/view/278">https://www.astmedj.ru/jour/article/view/278</self-uri><abstract><p>Актуальность темы обусловлена недостаточной информированностью врачей об опухоли Клацкина (воротной холангиокарциноме). Это связано с весьма редкой встречаемостью заболевания и слабой ознакомленностью практических врачей, особенно терапевтов, с клиническими проявлениями, современными возможностями дифференциальной диагностики и методами лечения данной патологии. Описан клинический случай воротной холангиокарциномы у мужчины 66 лет, рассмотрены трудности при установлении окончательного диагноза. Отражены особенности современных лабораторно-инструментальных методов медицинской визуализации и технологии интервенционных вмешательств и химиотерапии. Представлен клинический случай указанного заболевания.</p></abstract><trans-abstract xml:lang="en"><p>The relevance of the topic is caused by the insufficient acquaintance of Klatskin's tumor, or the portal cholangiocarcinoma, among the general practitioners, because of the evident rarity of the disease and poor information available for the practical doctors, especially internists, upon the modern opportunities of its clinical manifestations, differential diagnosis and methods of treatment of this pathology. Clinical observation of the portal cholangiocarcinoma at the man of 66 years old is described from the moment of the first complaints/ The difficulties at establishment of the final diagnosis, with the description of modern laboratory toolinstrumental methods of medical visualization, the technics of medical interventions and chemotherapy are represented. A clinical case of this disease is presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>холангиоцеллюлярная карцинома</kwd><kwd>опухоль Клацкина</kwd><kwd>диагностика</kwd><kwd>медицинская визуализация</kwd><kwd>лечение</kwd><kwd>осложнения</kwd><kwd>прогноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cholangiocellular carcinoma</kwd><kwd>Klatskin's tumor</kwd><kwd>diagnosis</kwd><kwd>medical visualization</kwd><kwd>treatment</kwd><kwd>complica-tions</kwd><kwd>prognosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Everhart J. E. and Ruhl C. E. Burden of digestive diseases in the United States part III : liver, biliary tract, and pancreas // Gastroenterology. 2009. Vol. 136, no. 4. P. 1134–1144.</mixed-citation><mixed-citation xml:lang="en">Everhart J. E., and Ruhl C. E. 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